SCHEMBL518043

SCHEMBL518043

O=C(NC1CCCCC1)c1ccc(-c2ccc(C(=O)NC3CCCCC3)cc2)cc1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 7/20 0.74
RAB9A P51151 7/20 0.74
SMN1; SMN2 Q16637 5/20 0.74
HPGD P15428 3/20 0.74
CYP1A2 P05177 1/20 0.74
CYP2C19 P33261 1/20 0.74
KMT2A Q03164 3/20 0.71
MEN1 O00255 1/20 0.71
PTPN1 P18031 1/20 0.68
PTPN11 Q06124 1/20 0.68
MAOA P21397 1/20 0.64
MAOB P27338 1/20 0.64
LMNA P02545 1/20 0.62
SMYD3 Q9H7B4 1/20 0.61
ALDH1A1 P00352 2/20 0.59
NPSR1 Q6W5P4 1/20 0.59
HDAC4 P56524 1/20 0.58
TP53 P04637 1/20 0.58
NFKB1 P19838 1/20 0.58
NFKB2 Q00653 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL517178 1.00 NPC1 (0.74) NPC1RAB9ASMN1; SMN2HPGDCYP1A2
SCHEMBL29927547 1.00 NPC1 (0.74) NPC1RAB9ASMN1; SMN2HPGDCYP1A2
SCHEMBL517912 1.00 NPC1 (0.74) NPC1RAB9ASMN1; SMN2HPGDCYP1A2
SCHEMBL517452 0.98 NPC1 (0.73) NPC1RAB9ASMN1; SMN2HPGDCYP1A2
SCHEMBL520877 0.94 NPC1 (0.82) NPC1RAB9ASMN1; SMN2HPGDCYP1A2
SCHEMBL28928584 0.94 NPC1 (0.82) NPC1RAB9ASMN1; SMN2HPGDCYP1A2
SCHEMBL126657 0.94 NPC1 (0.82) NPC1RAB9ASMN1; SMN2HPGDCYP1A2
SCHEMBL2983895 0.93 NPC1 (0.84) NPC1RAB9ASMN1; SMN2HPGDCYP1A2
SCHEMBL22308180 0.93 NPC1 (0.84) NPC1RAB9ASMN1; SMN2HPGDCYP1A2
SCHEMBL22289346 0.93 NPC1 (0.84) NPC1RAB9ASMN1; SMN2HPGDCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021069690-A1 FILM THAI POLYETHYLENE CO., LTD. (TH) 2021-04-15 WO claimed
US-10011709-B2 Compositions comprising propylene-based elastomers and polyalphaolefins EXXONMOBIL CHEMICAL PATENTS INC. (US) 2018-07-03 US claimed
US-20170362421-A1 Compositions Comprising Propylene-Based Elastomers and Polyalphaolefins EXXONMOBIL CHEMICAL PATENTS INC. (US) 2017-12-21 US claimed
WO-2016137559-A1 COMPOSITIONS COMPRISING PROPYLENE-BASED ELASTOMERS AND POLYALPHAOLEFINS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2016-09-01 WO claimed
US-6235823-B1 CRYSTALLINE POLYPROPLYLENE RESIN AND A BETA-NUCLEATING AGENT, THE BETA-NUCLEATING AGENT BEING A DIAMIDE COMPOUND. NEW JAPAN CHEMICAL CO., LTD. (JP) 2001-05-22 US claimed
EP-0557721-B1 Polypropylene moulded articles with increased -crystal content and bisamides as -nucleating agents. NEW JAPAN CHEM CO LTD (JP) 2000-10-04 EP claimed
EP-0557721-A2 Crystalline polypropylene resin composition and amide compounds NEW JAPAN CHEMICAL CO.,LTD. (JP) 1993-09-01 EP claimed
WO-2021069690-A1 FILM THAI POLYETHYLENE CO., LTD. (TH) 2021-04-15 WO disclosed
US-10011709-B2 Compositions comprising propylene-based elastomers and polyalphaolefins EXXONMOBIL CHEMICAL PATENTS INC. (US) 2018-07-03 US disclosed
EP-2392458-B1 POLYPROPYLENE RESIN MOLDED ARTICLE NEW JAPAN CHEM CO LTD (JP) 2018-03-14 EP disclosed
US-20170362421-A1 Compositions Comprising Propylene-Based Elastomers and Polyalphaolefins EXXONMOBIL CHEMICAL PATENTS INC. (US) 2017-12-21 US disclosed
WO-2016137559-A1 COMPOSITIONS COMPRISING PROPYLENE-BASED ELASTOMERS AND POLYALPHAOLEFINS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2016-09-01 WO disclosed
US-9287543-B2 Porous film, separator for electric storage device, and electric storage device TORAY INDUSTRIES, INC. (JP) 2016-03-15 US disclosed
EP-0790262-B1 PROPYLENE-ETHYLENE COPOLYMER COMPOSITIONS AND PROCESS FOR THE PRODUCTION THEREOF CHISSO CORP (JP) 2000-05-10 EP disclosed
US-6005034-A POLYMER MELTS OF ETHYLENE-PROPYLENE COPOLYMERS CHISSO CORPOATION (JP) 1999-12-21 US disclosed
EP-0962489-A2 Crystalline polypropylene resin composition and amide compounds NEW JAPAN CHEMICAL CO.,LTD. (JP) 1999-12-08 EP disclosed
US-5716998-A PARTICLES COMPRISING POLYPROPYLENE RESIN AND DIAMIDE COMPOUND AS BETA-FORM NUCLEATING AGENT KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1998-02-10 US disclosed
EP-0790262-A1 PROPYLENE-ETHYLENE COPOLYMER COMPOSITIONS AND PROCESS FOR THE PRODUCTION THEREOF CHISSO CORPORATION (JP) 1997-08-20 EP disclosed
EP-0790275-A1 PREFOAMED PARTICLES OF POLYPROPYLENE RESIN AND PROCESS FOR PRODUCING THE SAME KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1997-08-20 EP disclosed
EP-0557721-A2 Crystalline polypropylene resin composition and amide compounds NEW JAPAN CHEMICAL CO.,LTD. (JP) 1993-09-01 EP disclosed