Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.73 |
| ▸ | RAB9A | P51151 | 5/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.73 |
| ▸ | MEN1 | O00255 | 1/20 | 0.73 |
| ▸ | HPGD | P15428 | 2/20 | 0.71 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.71 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.71 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.65 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.65 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.63 |
| ▸ | MAOA | P21397 | 1/20 | 0.61 |
| ▸ | MAOB | P27338 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29927547 | 0.98 | NPC1 (0.74) | NPC1RAB9ASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL517912 | 0.98 | NPC1 (0.74) | NPC1RAB9ASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL518043 | 0.98 | NPC1 (0.74) | NPC1RAB9ASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL517178 | 0.98 | NPC1 (0.74) | NPC1RAB9ASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL123652 | 0.94 | NPC1 (0.79) | NPC1RAB9ASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL8161568 | 0.93 | NPC1 (0.87) | NPC1RAB9ASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL126657 | 0.92 | NPC1 (0.82) | NPC1RAB9ASMN1; SMN2KMT2AHPGD | |
| SCHEMBL28928584 | 0.92 | NPC1 (0.82) | NPC1RAB9ASMN1; SMN2KMT2AHPGD | |
| SCHEMBL520877 | 0.92 | NPC1 (0.82) | NPC1RAB9ASMN1; SMN2KMT2AHPGD | |
| SCHEMBL2983895 | 0.91 | NPC1 (0.84) | NPC1RAB9ASMN1; SMN2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2392458-B1 | POLYPROPYLENE RESIN MOLDED ARTICLE | NEW JAPAN CHEM CO LTD (JP) | 2018-03-14 | — | — | EP | disclosed |
| US-9287543-B2 | Porous film, separator for electric storage device, and electric storage device | TORAY INDUSTRIES, INC. (JP) | 2016-03-15 | — | — | US | disclosed |
| US-9023921-B2 | Method for inhibiting crystal growth rate of amide compound and method for producing molded article of polyolefin-based resin | NEW JAPAN CHEMICAL CO., LTD. (JP) | 2015-05-05 | — | — | US | disclosed |
| EP-2671909-A1 | POROUS FILM, SEPARATOR FOR ELECTRICITY-STORING DEVICE, AND ELECTRICITY-STORING DEVICE | Toray Industries, Inc. (JP) | 2013-12-11 | — | — | EP | disclosed |
| US-20130316246-A1 | POROUS FILM, SEPARATOR FOR ELECTRIC STORAGE DEVICE, AND ELECTRIC STORAGE DEVICE | TORAY INDUSTRIES, INC. (JP) | 2013-11-28 | — | — | US | disclosed |
| EP-2431415-A1 | METHOD FOR CONTROLLING CRYSTAL GROWTH RATE OF AMIDE COMPOUND AND METHOD FOR PRODUCING MOLDED ARTICLE OF POLYOLEFIN-BASED RESIN | New Japan Chemical Co., Ltd. (JP) | 2012-03-21 | — | — | EP | disclosed |
| US-20120035304-A1 | METHOD FOR INHIBITING CRYSTAL GROWTH RATE OF AMIDE COMPOUND AND METHOD FOR PRODUCING MOLDED ARTICLE OF POLYOLEFIN-BASED RESIN | NEW JAPAN CHEMICAL CO., LTD. (JP) | 2012-02-09 | — | — | US | disclosed |
| US-20120028006-A1 | POLYPROPYLENE RESIN MOLDED ARTICLE | NEW JAPAN CHEMICAL CO., LTD. (JP) | 2012-02-02 | — | — | US | disclosed |
| EP-2392458-A2 | POLYPROPYLENE RESIN MOLDED ARTICLE | New Japan Chemical Co., Ltd. (JP) | 2011-12-07 | — | — | EP | disclosed |
| EP-0962489-B1 | Crystalline polypropylene resin composition and amide compounds | NEW JAPAN CHEM CO LTD (JP) | 2004-09-15 | — | — | EP | disclosed |
| US-6235823-B1 | CRYSTALLINE POLYPROPLYLENE RESIN AND A BETA-NUCLEATING AGENT, THE BETA-NUCLEATING AGENT BEING A DIAMIDE COMPOUND. | NEW JAPAN CHEMICAL CO., LTD. (JP) | 2001-05-22 | — | — | US | disclosed |
| EP-0557721-B1 | Polypropylene moulded articles with increased -crystal content and bisamides as -nucleating agents. | NEW JAPAN CHEM CO LTD (JP) | 2000-10-04 | — | — | EP | disclosed |
| EP-0962489-A2 | Crystalline polypropylene resin composition and amide compounds | NEW JAPAN CHEMICAL CO.,LTD. (JP) | 1999-12-08 | — | — | EP | disclosed |
| EP-0557721-A2 | Crystalline polypropylene resin composition and amide compounds | NEW JAPAN CHEMICAL CO.,LTD. (JP) | 1993-09-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120035304-A1 | METHOD FOR INHIBITING CRYSTAL GROWTH RATE OF AMIDE COMPOUND AND METHOD FOR PRODUCING MOLDED ARTICLE OF POLYOLEFIN-BASED RESIN | MNAT1, RFT1, RTF1 | NPC1 2313/4885RAB9A 4496/4885SMN1; SMN2 3244/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.