Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.82 |
| ▸ | RAB9A | P51151 | 7/20 | 0.82 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.82 |
| ▸ | HPGD | P15428 | 4/20 | 0.82 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.82 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.82 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.72 |
| ▸ | MAOA | P21397 | 1/20 | 0.70 |
| ▸ | MAOB | P27338 | 1/20 | 0.70 |
| ▸ | LMNA | P02545 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.64 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.63 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.63 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.63 |
| ▸ | RELA | Q04206 | 1/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL126657 | 1.00 | NPC1 (0.82) | NPC1RAB9ASMN1; SMN2HPGDCYP1A2 | |
| SCHEMBL28928584 | 1.00 | NPC1 (0.82) | NPC1RAB9ASMN1; SMN2HPGDCYP1A2 | |
| SCHEMBL123652 | 0.98 | NPC1 (0.79) | NPC1RAB9ASMN1; SMN2HPGDCYP1A2 | |
| SCHEMBL518043 | 0.94 | NPC1 (0.74) | NPC1RAB9ASMN1; SMN2HPGDCYP1A2 | |
| SCHEMBL29927547 | 0.94 | NPC1 (0.74) | NPC1RAB9ASMN1; SMN2HPGDCYP1A2 | |
| SCHEMBL517178 | 0.94 | NPC1 (0.74) | NPC1RAB9ASMN1; SMN2HPGDCYP1A2 | |
| SCHEMBL517912 | 0.94 | NPC1 (0.74) | NPC1RAB9ASMN1; SMN2HPGDCYP1A2 | |
| SCHEMBL16583892 | 0.92 | NPC1 (0.72) | NPC1RAB9ASMN1; SMN2HPGDCYP1A2 | |
| SCHEMBL2916169 | 0.92 | NPC1 (0.72) | NPC1RAB9ASMN1; SMN2HPGDCYP1A2 | |
| SCHEMBL16589422 | 0.92 | NPC1 (0.72) | NPC1RAB9ASMN1; SMN2HPGDCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2392458-B1 | POLYPROPYLENE RESIN MOLDED ARTICLE | NEW JAPAN CHEM CO LTD (JP) | 2018-03-14 | — | — | EP | disclosed |
| US-20120028006-A1 | POLYPROPYLENE RESIN MOLDED ARTICLE | NEW JAPAN CHEMICAL CO., LTD. (JP) | 2012-02-02 | — | — | US | disclosed |
| EP-2392458-A2 | POLYPROPYLENE RESIN MOLDED ARTICLE | New Japan Chemical Co., Ltd. (JP) | 2011-12-07 | — | — | EP | disclosed |