Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.56 |
| ▸ | PGR | P06401 | 1/20 | 0.56 |
| ▸ | SRC | P12931 | 1/20 | 0.48 |
| ▸ | MAP3K5 | Q99683 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CASP1 | P29466 | 2/20 | 0.44 |
| ▸ | BRCA1 | P38398 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | CASP7 | P55210 | 2/20 | 0.44 |
| ▸ | YWHAG | P61981 | 1/20 | 0.44 |
| ▸ | HBB | P68871 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5165239 | 0.88 | MEN1 (0.56) | MEN1KMT2APGRSRCMAP3K5 | |
| SCHEMBL5167153 | 0.82 | MEN1 (0.70) | MEN1KMT2APGRSRCMAP3K5 | |
| SCHEMBL5165191 | 0.81 | KMT2A (0.58) | MEN1KMT2APGRSRCMAP3K5 | |
| SCHEMBL5164479 | 0.81 | MEN1 (0.58) | MEN1KMT2APGRSRCMAP3K5 | |
| SCHEMBL5166407 | 0.81 | MEN1 (0.58) | MEN1KMT2APGRSRCMAP3K5 | |
| SCHEMBL5165395 | 0.78 | MEN1 (0.43) | MEN1KMT2APGRMAP3K5MAPT | |
| SCHEMBL5164579 | 0.77 | MEN1 (0.43) | MEN1KMT2APGRMAP3K5MAPT | |
| SCHEMBL7721669 | 0.77 | HDAC4 (0.55) | MEN1KMT2APGRSRCMAPT | |
| SCHEMBL5165180 | 0.76 | MEN1 (0.47) | MEN1KMT2APGRMAP3K5MAPT | |
| SCHEMBL10677667 | 0.76 | KMT2A (0.71) | MEN1KMT2APGRSRCL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1224172-B1 | DRUGS FOR THE TREATMENT OF MALIGNANT TUMOURS | ACTIVE BIOTECH AB (SE) | 2007-04-04 | — | — | EP | disclosed |
| US-6395750-B1 | Includes laquinimod, N-ethyl-N-phenyl-1,2-dihydro-4-hydroxy-5-chloro-1-methyl-2-oxo-quinoline-3-carboxamide and its salts; breat or prostate cancer | ACTIVE BIOTECH AB (SE) | 2002-05-28 | — | — | US | disclosed |