Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 4/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | RXFP3 | Q9NSD7 | 1/20 | 0.32 |
| ▸ | ALPL | P05186 | 1/20 | 0.31 |
| ▸ | ALPI | P09923 | 1/20 | 0.31 |
| ▸ | ALPG | P10696 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4185993 | 0.80 | SMN1; SMN2 (0.35) | MTNR1AMTNR1BMAPTALDH1A1KDM4E | |
| SCHEMBL4185988 | 0.80 | SMN1; SMN2 (0.35) | MTNR1AMTNR1BMAPTALDH1A1KDM4E | |
| SCHEMBL4179681 | 0.78 | KDM4E (0.39) | MAPTALDH1A1KDM4ELMNARAB9A | |
| SCHEMBL4179685 | 0.78 | KDM4E (0.39) | MAPTALDH1A1KDM4ELMNARAB9A | |
| SCHEMBL12123685 | 0.77 | MAPT (0.39) | MTNR1AMTNR1BMAPTALDH1A1KDM4E | |
| SCHEMBL4179754 | 0.75 | HTR6 (0.39) | MTNR1AMTNR1BALDH1A1KDM4ENPC1 | |
| SCHEMBL5180273 | 0.73 | ALDH1A1 (0.44) | MAPTALDH1A1KDM4ESMN1; SMN2MEN1 | |
| SCHEMBL5180267 | 0.73 | ALDH1A1 (0.44) | MAPTALDH1A1KDM4ESMN1; SMN2MEN1 | |
| SCHEMBL4193434 | 0.71 | — | — | |
| SCHEMBL4193429 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1414440-B1 | N-PHENYLPYRROLE GUANIDINE DERIVATIVES AS MELANOCORTIN RECEPTOR LIGANDS | ACTION PHARMA AS (DK) | 2007-01-10 | — | — | EP | claimed |
| US-20060148798-A1 | N-phenylpyrrole guanidine derivatives as melanocortin receptor ligands | ACTION PHARMA A/S (DK) | 2006-07-06 | — | — | US | claimed |
| EP-1414440-B1 | N-PHENYLPYRROLE GUANIDINE DERIVATIVES AS MELANOCORTIN RECEPTOR LIGANDS | ACTION PHARMA AS (DK) | 2007-01-10 | — | — | EP | disclosed |
| US-20060148798-A1 | N-phenylpyrrole guanidine derivatives as melanocortin receptor ligands | ACTION PHARMA A/S (DK) | 2006-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060148798-A1 | N-phenylpyrrole guanidine derivatives as melanocortin receptor ligands | MC1R, MC5R, MC3R | MTNR1A 42/4885MTNR1B 50/4885MAPT 3844/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.