Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.59 |
| ▸ | MEN1 | O00255 | 5/20 | 0.59 |
| ▸ | NPC1 | O15118 | 3/20 | 0.59 |
| ▸ | KDR | P35968 | 5/20 | 0.58 |
| ▸ | ABL1 | P00519 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.53 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.53 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.53 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.53 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.53 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5180990 | 0.87 | MAPT (0.64) | KMT2AMEN1NPC1TP53RAB9A | |
| SCHEMBL22192224 | 0.87 | MAPT (0.64) | KMT2AMEN1NPC1TP53RAB9A | |
| SCHEMBL5181338 | 0.87 | THRB (0.75) | THRBKMT2AMEN1SMN1; SMN2NR1H4 | |
| SCHEMBL8770602 | 0.83 | GAA (0.64) | KMT2AMEN1NPC1TP53RAB9A | |
| SCHEMBL28661625 | 0.80 | MAPT (0.47) | KMT2AMEN1NPC1TP53RAB9A | |
| SCHEMBL29754291 | 0.80 | MAPT (0.47) | KMT2AMEN1NPC1TP53RAB9A | |
| SCHEMBL22192232 | 0.80 | SMN1; SMN2 (0.62) | KMT2AMEN1NPC1TP53RAB9A | |
| SCHEMBL7806507 | 0.79 | TP53 (0.70) | KMT2AMEN1NPC1TP53RAB9A | |
| SCHEMBL5182631 | 0.79 | THRB (0.64) | THRBKMT2AMEN1NPC1TP53 | |
| SCHEMBL28687707 | 0.79 | NPC1 (0.63) | THRBKMT2AMEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1526149-B1 | Aromatic amide block copolymer and process of producing the same | TOSOH CORP (JP) | 2007-05-23 | — | — | EP | disclosed |
| US-7129314-B2 | Aromatic amide block copolymer and process of producing the same | TOSOH CORPORATION (JP) | 2006-10-31 | — | — | US | disclosed |
| US-20050090639-A1 | Aromatic amide block copolymer and process of producing the same | TOSOH CORPORATION (JP) | 2005-04-28 | — | — | US | disclosed |
| EP-1526149-A1 | Aromatic amide block copolymer and process of producing the same | Tosoh Corporation (JP) | 2005-04-27 | — | — | EP | disclosed |