SCHEMBL5180990

SCHEMBL5180990

O=C(Nc1ccc(OCCO)cc1)c1ccc(C(=O)Nc2ccc(OCCO)cc2)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.64
RAB9A P51151 5/20 0.61
KDM4E B2RXH2 2/20 0.61
ALDH1A1 P00352 2/20 0.61
TSHR P16473 2/20 0.61
HSD17B10 Q99714 2/20 0.61
MCL1 Q07820 1/20 0.61
NPC1 O15118 7/20 0.60
CYP1A2 P05177 1/20 0.60
SMN1; SMN2 Q16637 5/20 0.60
LMNA P02545 2/20 0.60
STAT3 P40763 1/20 0.60
TP53 P04637 2/20 0.59
ALOX15 P16050 1/20 0.59
MCHR1 Q99705 2/20 0.58
KMT2A Q03164 3/20 0.56
GAA P10253 1/20 0.56
MEN1 O00255 1/20 0.56
XDH P47989 1/20 0.55
POLB P06746 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22192224 1.00 MAPT (0.64) MAPTRAB9AKDM4EALDH1A1TSHR
SCHEMBL8770602 0.95 GAA (0.64) MAPTRAB9AKDM4EALDH1A1TSHR
SCHEMBL22192232 0.92 SMN1; SMN2 (0.62) MAPTRAB9AKDM4EALDH1A1TSHR
SCHEMBL7294640 0.90 TRPV1 (0.63) MAPTRAB9AKDM4EALDH1A1TSHR
SCHEMBL22192247 0.87 KMT2A (0.56) MAPTRAB9AKDM4EALDH1A1TSHR
SCHEMBL5181024 0.87 THRB (0.60) MAPTRAB9ANPC1SMN1; SMN2TP53
SCHEMBL1663757 0.86 NPC1 (0.54) MAPTRAB9AKDM4EALDH1A1TSHR
SCHEMBL22192244 0.85 MAPT (0.57) MAPTRAB9AKDM4EALDH1A1TSHR
SCHEMBL22192236 0.85 NPC1 (0.68) MAPTRAB9AKDM4EALDH1A1TSHR
SCHEMBL22192246 0.85 SMN1; SMN2 (0.81) MAPTRAB9AKDM4EALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1526149-B1 Aromatic amide block copolymer and process of producing the same TOSOH CORP (JP) 2007-05-23 EP disclosed
US-7129314-B2 Aromatic amide block copolymer and process of producing the same TOSOH CORPORATION (JP) 2006-10-31 US disclosed
US-20050090639-A1 Aromatic amide block copolymer and process of producing the same TOSOH CORPORATION (JP) 2005-04-28 US disclosed
EP-1526149-A1 Aromatic amide block copolymer and process of producing the same Tosoh Corporation (JP) 2005-04-27 EP disclosed