SCHEMBL5181997

SCHEMBL5181997

C=C/C(C(=O)O)=C(\C=C)C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.53
ALDH1A1 P00352 4/20 0.41
TSHR P16473 3/20 0.41
FGFR4 P22455 1/20 0.41
MAPK1 P28482 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
ALOX15 P16050 1/20 0.38
HSD17B10 Q99714 1/20 0.38
AKT1 P31749 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9499003 1.00 LMNA (0.53) LMNAALDH1A1TSHRFGFR4MAPK1
SCHEMBL9498997 1.00 LMNA (0.53) LMNAALDH1A1TSHRFGFR4MAPK1
Ethylene SCHEMBL27692988 0.96 LMNA (0.50) LMNAALDH1A1TSHRFGFR4MAPK1
SCHEMBL23378672 0.85 LMNA (0.40) LMNAALDH1A1TSHRFGFR4MAPK1
SCHEMBL5327633 0.83
SCHEMBL18994000 0.83 LMNA (0.44) LMNAALDH1A1TSHRFGFR4MAPK1
SCHEMBL19068607 0.81 LMNA (0.36) LMNAALDH1A1
SCHEMBL896153 0.78 ALDH1A1 (0.45) LMNAALDH1A1TSHRFGFR4MAPK1
SCHEMBL20861922 0.78 ALDH1A1 (0.45) LMNAALDH1A1TSHRFGFR4MAPK1
SCHEMBL8664423 0.78 ALDH1A1 (0.45) LMNAALDH1A1TSHRFGFR4MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3551675-B1 RESIN COMPOSITIONS NOVOSET LLC (US) 2022-11-09 EP disclosed
EP-3781622-B1 ADHESIVE COMPOSITIONS WITH A GELCONTENT FROM CROSSLINKING OF KETO- OR ALDEHYDE GROUPS BASF SE (DE) 2022-10-12 EP disclosed
EP-3067373-B1 METHOD FOR PRODUCING VINYLAMINE (CO)POLYMER MITSUBISHI CHEM CORP (JP) 2018-06-20 EP disclosed
EP-3067373-A1 METHOD FOR PRODUCING VINYLAMINE (CO)POLYMER Mitsubishi Rayon Co., Ltd. (JP) 2016-09-14 EP disclosed
US-20160237191-A1 METHOD FOR PRODUCING VINYLAMINE (CO)POLYMER MITSUBISHI RAYON CO., LTD. (JP) 2016-08-18 US disclosed
CN-101687698-B Glass fiber sizing agent containing amphoteric polymer compound NITTO BOSEKI CO LTD 2012-08-01 CN disclosed
CN-101687698-A Glass fiber sizing agent containing amphoteric polymer compound NITTO BOSEKI CO LTD 2010-03-31 CN disclosed
EP-1796459-A2 FUNGICIDALLY ACTIVE POLYMER DISPERSIONS AND USE THEREOF Celanese Emulsions GmbH (DE) 2007-06-20 EP disclosed
WO-2006034762-A2 FUNGICIDALLY ACTIVE POLYMER DISPERSIONS AND USE THEREOF CELANESE EMULSIONS GMBH (DE) 2006-04-06 WO disclosed
CN-1228050-A Chemical treatment of fibers and spun composite strands for molded fiber reinforced thermoplastic composite articles OWENS CORNING FIBERGLASS CORP (US) 1999-09-08 CN disclosed