Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.48 |
| ▸ | MAOB | P27338 | 3/20 | 0.44 |
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 2/20 | 0.41 |
| ▸ | DRD4 | P21917 | 2/20 | 0.41 |
| ▸ | DRD5 | P21918 | 2/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10703667 | 0.78 | DRD1 (0.55) | MAOBMAOASLC6A4DRD1DRD4 | |
| SCHEMBL3895372 | 0.74 | KMT2A (0.48) | KMT2AABCB1MAOBMAOASLC6A4 | |
| Fumaric Acid SCHEMBL10700517 | 0.71 | SMN1; SMN2 (0.52) | KMT2AMAOBMAOASLC6A4DRD1 | |
| Maleic Acid SCHEMBL10700510 | 0.71 | SMN1; SMN2 (0.52) | KMT2AMAOBMAOASLC6A4DRD1 | |
| SCHEMBL5471119 | 0.68 | KMT2A (0.43) | KMT2AABCB1MAOBMAOASLC6A4 | |
| SCHEMBL11169272 | 0.67 | MAOA (0.84) | KMT2AABCB1MAOBMAOASLC6A4 | |
| Hydrochloric Acid SCHEMBL11158000 | 0.66 | MAOA (0.81) | KMT2AABCB1MAOBMAOASLC6A4 | |
| SCHEMBL10702082 | 0.65 | ESR1 (0.50) | KMT2A | |
| SCHEMBL3903162 | 0.65 | MAOB (0.48) | KMT2AABCB1MAOBMAOASLC6A4 | |
| SCHEMBL18191166 | 0.64 | ABCB1 (1.00) | KMT2AABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1511727-B1 | AROMATIC SULFONES AND THEIR MEDICAL USE | GLAXO GROUP LTD (GB) | 2007-02-21 | — | — | EP | disclosed |