Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 4/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetamide SCHEMBL5182479 | 1.00 | BLM (0.35) | BLMLMNAALOX15PMP22PDE4A | |
| Acetic Acid SCHEMBL9302309 | 0.91 | CRBN (0.34) | PDE4APDE4BPDE4CPDE4DMTNR1A | |
| SCHEMBL164602 | 0.89 | — | — | |
| SCHEMBL164603 | 0.89 | — | — | |
| SCHEMBL351949 | 0.89 | — | — | |
| Hydrochloric Acid SCHEMBL20532011 | 0.86 | — | — | |
| Acetaldehyde SCHEMBL27601442 | 0.83 | MTNR1A (0.33) | PDE4APDE4BPDE4CPDE4DMTNR1A | |
| SCHEMBL17865758 | 0.72 | CRBN (0.59) | CRBN | |
| SCHEMBL13323289 | 0.71 | — | — | |
| SCHEMBL6021860 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1748981-A1 | PROCESS FOR THE PREPARATION OF OPTICALLY PURE 4-HYDROXY-2-OXO-1-PYRROLIDINE ACETAMIDE | AHN-Gook Pharmaceutical Co., Ltd. (KR) | 2007-02-07 | — | — | EP | disclosed |
| WO-2005115978-A1 | PROCESS FOR THE PREPARATION OF OPTICALLY PURE 4-HYDROXY-2-OXO-1-PYRROLIDINE ACETAMIDE | AHN-GOOK PHARMACEUTICAL CO., LTD. (KR) | 2005-12-08 | — | — | WO | disclosed |