Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.67 |
| ▸ | TPSD1 | Q9BZJ3 | 2/20 | 0.67 |
| ▸ | TPSG1 | Q9NRR2 | 2/20 | 0.67 |
| ▸ | FOLH1 | Q04609 | 6/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.47 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.47 |
| ▸ | SYK | P43405 | 1/20 | 0.46 |
| ▸ | KLK7 | P49862 | 1/20 | 0.45 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TGM2 | P21980 | 1/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5981757 | 0.89 | TPSAB1 (0.55) | TPSAB1TPSD1TPSG1FOLH1MAPT | |
| SCHEMBL2748058 | 0.89 | TPSAB1 (0.59) | TPSAB1TPSD1TPSG1FOLH1MAPT | |
| SCHEMBL18500333 | 0.88 | FOLH1 (0.65) | TPSAB1TPSD1TPSG1FOLH1MAPT | |
| SCHEMBL5174128 | 0.87 | SYK (0.55) | TPSAB1TPSD1TPSG1FOLH1MAPT | |
| SCHEMBL14561119 | 0.85 | FOLH1 (0.70) | TPSAB1TPSD1TPSG1FOLH1MAPT | |
| SCHEMBL28480221 | 0.85 | TPSAB1 (0.52) | TPSAB1TPSD1TPSG1FOLH1MAPT | |
| SCHEMBL1021829 | 0.85 | TPSAB1 (0.52) | TPSAB1TPSD1TPSG1FOLH1MAPT | |
| SCHEMBL5712142 | 0.85 | TPSAB1 (0.52) | TPSAB1TPSD1TPSG1FOLH1MAPT | |
| SCHEMBL3820596 | 0.84 | TPSAB1 (0.53) | TPSAB1TPSD1TPSG1FOLH1MAPT | |
| SCHEMBL375887 | 0.84 | TPSAB1 (0.53) | TPSAB1TPSD1TPSG1FOLH1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1797110-A1 | ANTIBACTERIAL AMIDE MACROCYCLES IV | AiCuris GmbH & Co. KG (DE) | 2007-06-20 | — | — | EP | disclosed |
| WO-2006034786-A1 | ANTIBACTERIAL AMIDE MACROCYCLES IV | AICURIS GMBH & CO.KG (DE) | 2006-04-06 | — | — | WO | disclosed |