Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.55 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.54 |
| ▸ | TPSD1 | Q9BZJ3 | 2/20 | 0.54 |
| ▸ | TPSG1 | Q9NRR2 | 2/20 | 0.54 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 3/20 | 0.41 |
| ▸ | CTSL | P07711 | 2/20 | 0.41 |
| ▸ | CTSB | P07858 | 2/20 | 0.41 |
| ▸ | CTSS | P25774 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5181769 | 0.93 | SYK (0.60) | SYKTPSAB1TPSD1TPSG1FOLH1 | |
| SCHEMBL5182247 | 0.87 | TPSAB1 (0.67) | SYKTPSAB1TPSD1TPSG1FOLH1 | |
| SCHEMBL18076338 | 0.84 | TPSAB1 (0.47) | SYKTPSAB1TPSD1TPSG1SMN1; SMN2 | |
| SCHEMBL5182680 | 0.84 | TPSAB1 (0.47) | SYKTPSAB1TPSD1TPSG1SMN1; SMN2 | |
| SCHEMBL19586697 | 0.82 | TPSAB1 (0.46) | SYKTPSAB1TPSD1TPSG1CTSK | |
| Water SCHEMBL1238348 | 0.81 | TPSAB1 (0.45) | SYKTPSAB1TPSD1TPSG1CTSK | |
| SCHEMBL17459537 | 0.81 | TPSAB1 (0.45) | SYKTPSAB1TPSD1TPSG1LMNA | |
| SCHEMBL2748058 | 0.80 | TPSAB1 (0.59) | SYKTPSAB1TPSD1TPSG1FOLH1 | |
| SCHEMBL1937057 | 0.80 | ABCB1 (0.46) | SYKTPSAB1TPSD1TPSG1 | |
| SCHEMBL212881 | 0.80 | SYK (0.55) | SYKTPSAB1TPSD1TPSG1FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1869068-A1 | ANTIBACTERIAL AMIDE-MACROCYCLES V | AiCuris GmbH & Co. KG (DE) | 2007-12-26 | — | — | EP | disclosed |
| EP-1797110-A1 | ANTIBACTERIAL AMIDE MACROCYCLES IV | AiCuris GmbH & Co. KG (DE) | 2007-06-20 | — | — | EP | disclosed |
| WO-2006103015-A1 | ANTIBACTERIAL AMIDE-MACROCYCLES V | AICURIS GMBH & CO. KG (DE) | 2006-10-05 | — | — | WO | disclosed |
| WO-2006034786-A1 | ANTIBACTERIAL AMIDE MACROCYCLES IV | AICURIS GMBH & CO.KG (DE) | 2006-04-06 | — | — | WO | disclosed |