Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | KDR | P35968 | 8/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 6/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 4/20 | 0.37 |
| ▸ | EGFR | P00533 | 2/20 | 0.37 |
| ▸ | FLT4 | P35916 | 3/20 | 0.37 |
| ▸ | FLT3 | P36888 | 3/20 | 0.37 |
| ▸ | KIT | P10721 | 2/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 2/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 6/20 | 0.34 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.33 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | CSF1R | P07333 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5183182 | 1.00 | MAOA (0.38) | MAOAMAOBKDRPDGFRBFGFR1 | |
| SCHEMBL5432281 | 0.95 | MAOA (0.42) | MAOAMAOBKDRPDGFRBFGFR1 | |
| SCHEMBL5432283 | 0.95 | MAOA (0.42) | MAOAMAOBKDRPDGFRBFGFR1 | |
| SCHEMBL5429372 | 0.86 | MAOA (0.51) | MAOAMAOBKDRPDGFRBFGFR1 | |
| SCHEMBL5429376 | 0.86 | MAOA (0.51) | MAOAMAOBKDRPDGFRBFGFR1 | |
| SCHEMBL7706676 | 0.82 | RET (0.39) | KDRFLT4FLT3KITCHEK1 | |
| SCHEMBL7706674 | 0.82 | RET (0.39) | KDRFLT4FLT3KITCHEK1 | |
| SCHEMBL5182966 | 0.81 | PIM1 (0.40) | KDRPDGFRBFLT4FLT3KIT | |
| SCHEMBL5182964 | 0.81 | PIM1 (0.40) | KDRPDGFRBFLT4FLT3KIT | |
| SCHEMBL5873921 | 0.78 | JAK3 (0.38) | KDRPDGFRBFGFR1FLT3CHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1773309-A1 | TAMOXIFEN RESPONSE IN PRE-AND POSTMENOPAUSAL BREAST CANCER PATIENTS | Forskarpatent i Syd AB (SE) | 2007-04-18 | — | — | EP | disclosed |
| WO-2006004545-A1 | TAMOXIFEN RESPONSE IN PRE-AND POSTMENOPAUSAL BREAST CANCER PATIENTS | FORSKARPATENT I SYD AB (SE) | 2006-01-12 | — | — | WO | disclosed |