Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 10/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 9/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.36 |
| ▸ | HTR3B | O95264 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.36 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2794665 | 0.82 | MEN1 (0.56) | MEN1KMT2ASLC6A4SLC6A2OPRD1 | |
| SCHEMBL7428163 | 0.79 | MEN1 (0.44) | MEN1KMT2ASLC6A4SLC6A2OPRD1 | |
| SCHEMBL1934346 | 0.74 | MEN1 (0.66) | MEN1KMT2ASLC6A4SLC6A2OPRD1 | |
| Hydrochloric Acid SCHEMBL27495835 | 0.73 | MEN1 (0.63) | MEN1KMT2ASLC6A4SLC6A2OPRD1 | |
| SCHEMBL9813071 | 0.69 | SIGMAR1 (0.41) | MEN1KMT2ASLC6A4SLC6A2OPRD1 | |
| SCHEMBL27664880 | 0.67 | MEN1 (0.42) | MEN1KMT2ASLC6A4SLC6A2OPRD1 | |
| SCHEMBL518318 | 0.65 | — | — | |
| SCHEMBL739058 | 0.64 | SIGMAR1 (0.52) | MEN1KMT2ASLC6A4SLC6A2SIGMAR1 | |
| SCHEMBL3208256 | 0.62 | CYP1A2 (0.63) | MEN1KMT2ACYP2D6KCNH2CYP2C9 | |
| SCHEMBL219432 | 0.62 | MEN1 (1.00) | MEN1KMT2ASLC6A4SLC6A2OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0479665-A2 | 1,4-Dihydropyridine derivatives, method for preparing the same and use thereof | TEIKOKU CHEMICAL INDUSTRIES CO., LTD. (JP) | 1992-04-08 | — | — | EP | disclosed |