Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 5/20 | 0.64 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.64 |
| ▸ | GRM3 | Q14832 | 3/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.64 |
| ▸ | LMNA | P02545 | 3/20 | 0.64 |
| ▸ | GRM8 | O00222 | 2/20 | 0.64 |
| ▸ | GRM6 | O15303 | 2/20 | 0.64 |
| ▸ | GRM5 | P41594 | 2/20 | 0.64 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | MTOR | P42345 | 1/20 | 0.64 |
| ▸ | PLCB1 | Q9NQ66 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.50 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.50 |
| ▸ | GSR | P00390 | 1/20 | 0.50 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.50 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4835874 | 0.80 | GRM4 (1.00) | GRM4GRM2GRM3CYP1A2ALOX15 | |
| SCHEMBL3125919 | 0.80 | GRM4 (1.00) | GRM4GRM2GRM3CYP1A2ALOX15 | |
| SCHEMBL179741 | 0.80 | GRM4 (1.00) | GRM4GRM2GRM3CYP1A2ALOX15 | |
| SCHEMBL235442 | 0.80 | GRM4 (1.00) | GRM4GRM2GRM3CYP1A2ALOX15 | |
| SCHEMBL719389 | 0.80 | GRM4 (1.00) | GRM4GRM2GRM3CYP1A2ALOX15 | |
| SCHEMBL2157698 | 0.80 | GRM4 (1.00) | GRM4GRM2GRM3CYP1A2ALOX15 | |
| SCHEMBL935371 | 0.80 | GRM4 (1.00) | GRM4GRM2GRM3CYP1A2ALOX15 | |
| SCHEMBL481144 | 0.80 | GRM4 (1.00) | GRM4GRM2GRM3CYP1A2ALOX15 | |
| Glutamic Acid SCHEMBL9280469 | 0.71 | GRM8 (0.75) | GRM4GRM2GRM3CYP1A2ALOX15 | |
| D-Glutamate SCHEMBL17127348 | 0.71 | GRM8 (1.00) | GRM4GRM2GRM3CYP1A2ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1121436-B1 | NON-DESENSITIZING AMPA-RECEPTORS | MAX PLANCK GESELLSCHAFT (DE) | 2007-06-27 | — | — | EP | disclosed |