Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM8 | O00222 | 2/20 | 0.75 |
| ▸ | GRM6 | O15303 | 2/20 | 0.75 |
| ▸ | GRM7 | Q14831 | 2/20 | 0.75 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.75 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.75 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.75 |
| ▸ | GSR | P00390 | 1/20 | 0.75 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.75 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.75 |
| ▸ | GRM5 | P41594 | 1/20 | 0.75 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.75 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.75 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.75 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.75 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.75 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.75 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.75 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.75 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.75 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glutamic Acid SCHEMBL5704264 | 0.87 | GRM8 (1.00) | GRM8GRM6GRM7GRM4GRIN2D | |
| Glutamic Acid SCHEMBL1554237 | 0.87 | GRM8 (1.00) | GRM8GRM6GRM7GRM4GRIN2D | |
| D-Glutamate SCHEMBL1330917 | 0.87 | GRM8 (1.00) | GRM8GRM6GRM7GRM4GRIN2D | |
| D-Glutamate SCHEMBL1332144 | 0.87 | GRM8 (1.00) | GRM8GRM6GRM7GRM4GRIN2D | |
| Glutamic Acid SCHEMBL2202 | 0.87 | GRM8 (1.00) | GRM8GRM6GRM7GRM4GRIN2D | |
| D-Glutamate SCHEMBL410241 | 0.87 | GRM8 (1.00) | GRM8GRM6GRM7GRM4GRIN2D | |
| D-Glutamate SCHEMBL1330566 | 0.87 | GRM8 (1.00) | GRM8GRM6GRM7GRM4GRIN2D | |
| D-Glutamate SCHEMBL1332007 | 0.87 | GRM8 (1.00) | GRM8GRM6GRM7GRM4GRIN2D | |
| D-Glutamate SCHEMBL43222 | 0.87 | GRM8 (1.00) | GRM8GRM6GRM7GRM4GRIN2D | |
| D-Glutamate SCHEMBL1332297 | 0.87 | GRM8 (1.00) | GRM8GRM6GRM7GRM4GRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114127974-B | Markers for labeling biomolecules | 上海宸安生物科技有限公司 | 2023-04-18 | — | — | CN | disclosed |
| CN-114127974-A | Markers for labeling biomolecules | 上海宸安生物科技有限公司 | 2022-03-01 | — | — | CN | disclosed |
| US-10030103-B2 | Stable helical ionic polypeptides | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2018-07-24 | — | — | US | disclosed |
| EP-2646048-B1 | STABLE HELICAL IONIC POLYPEPTIDES | UNIV ILLINOIS (US) | 2017-11-01 | — | — | EP | disclosed |
| US-20160215093-A1 | STABLE HELICAL IONIC POLYPEPTIDES | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2016-07-28 | — | — | US | disclosed |
| US-9243040-B2 | Stable helical ionic polypeptides | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2016-01-26 | — | — | US | disclosed |
| US-20130274173-A1 | STABLE HELICAL IONIC POLYPEPTIDES | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2013-10-17 | — | — | US | disclosed |
| EP-2646048-A2 | STABLE HELICAL IONIC POLYPEPTIDES | The Board of Trustees of the University of Illinois (US) | 2013-10-09 | — | — | EP | disclosed |
| WO-2012075147-A2 | STABLE HELICAL IONIC POLYPEPTIDES | BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2012-06-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10030103-B2 | Stable helical ionic polypeptides | GHITM, SLC7A1, PICALM | GRM8 3859/4885GRM6 1569/4885GRM7 1577/4885 |
| US-20130274173-A1 | STABLE HELICAL IONIC POLYPEPTIDES | GHITM, SLC7A1, PICALM | GRM8 3859/4885GRM6 1569/4885GRM7 1577/4885 |
| US-20160215093-A1 | STABLE HELICAL IONIC POLYPEPTIDES | GHITM, SLC7A1, PICALM | GRM8 3859/4885GRM6 1569/4885GRM7 1577/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.