Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.36 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.36 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | AKT1 | P31749 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ERN1 | O75460 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1682725 | 0.81 | PDE2A (0.35) | ADRA2AADRA1ABLM | |
| SCHEMBL12190518 | 0.77 | P2RX3 (0.48) | MGAMGAASIMGAM2P2RX3 | |
| SCHEMBL2937347 | 0.72 | LMNA (0.46) | P2RX3P2RX2MAPK1LMNAHTT | |
| SCHEMBL5184653 | 0.71 | CA1 (0.46) | MGAMGAASIMGAM2LMNA | |
| SCHEMBL23666032 | 0.70 | GAA (0.48) | MGAMGAASIMGAM2P2RX3 | |
| SCHEMBL16160619 | 0.69 | P2RX3 (0.41) | GAAP2RX3P2RX2MAPK1LMNA | |
| SCHEMBL26402157 | 0.69 | P2RX3 (0.36) | GAAP2RX3P2RX2STING1HTT | |
| SCHEMBL20794220 | 0.68 | GAA (0.43) | MGAMGAASIMGAM2P2RX3 | |
| SCHEMBL2001415 | 0.68 | LMNA (0.43) | P2RX3P2RX2MAPK1LMNAHTT | |
| SCHEMBL16173475 | 0.68 | CYP3A4 (0.43) | MAPK1LMNAHTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1844026-A2 | MORPHOLINES AS 5HT2C AGONISTS | F.HOFFMANN-LA ROCHE AG (CH) | 2007-10-17 | — | — | EP | disclosed |
| WO-2006077025-A2 | MORPHOLINES AS 5HT2C AGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2006-07-27 | — | — | WO | disclosed |