Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA1 | P02708 | 1/20 | 0.49 |
| ▸ | CHRNG | P07510 | 1/20 | 0.49 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.49 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.49 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.49 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | CHRND | Q07001 | 1/20 | 0.49 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6400223 | 0.77 | VCAM1 (0.41) | LMNAMAPTALDH1A1 | |
| SCHEMBL6400535 | 0.76 | TDP1 (0.41) | TSHRLMNASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL10184986 | 0.71 | TSHR (0.57) | CHRNA1CHRNGCHRNB1CHRNB2SLC6A2 | |
| SCHEMBL14253687 | 0.70 | KDM1A (0.53) | CHRNA1CHRNGCHRNB1CHRNB2SLC6A2 | |
| SCHEMBL6401065 | 0.70 | CHRNA1 (0.39) | CHRNA1CHRNGCHRNB1CHRNB2SLC6A2 | |
| SCHEMBL16824941 | 0.69 | KDM1A (0.55) | CHRNA1CHRNGCHRNB1CHRNB2SLC6A2 | |
| SCHEMBL26218870 | 0.68 | KDM1A (0.54) | CHRNA1CHRNGCHRNB1CHRNB2SLC6A2 | |
| Dinitrophenylene SCHEMBL27442892 | 0.67 | TSHR (0.85) | TSHRLMNASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL28007654 | 0.67 | KDM1A (0.53) | CHRNA1CHRNGCHRNB1CHRNB2SLC6A2 | |
| SCHEMBL26218874 | 0.67 | KDM1A (0.53) | CHRNA1CHRNGCHRNB1CHRNB2SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1583967-B1 | METHOD FOR INHIBITING THE REPLICATION OF HERPES VIRUSES | AICURIS GMBH & CO KG (DE) | 2007-06-27 | — | — | EP | disclosed |
| US-20070004735-A1 | Method for inhibiting the replication of herpes viruses | AICURIS GMBH & CO. KG (DE) | 2007-01-04 | — | — | US | disclosed |
| EP-1583967-A2 | METHOD FOR INHIBITING THE REPLICATION OF HERPES VIRUSES | Bayer HealthCare AG (DE) | 2005-10-12 | — | — | EP | disclosed |
| US-20050059658-A1 | Pyridazinone | BAYER AKTIENGESELLSCHAFT (DE) | 2005-03-17 | — | — | US | disclosed |
| WO-2004060860-A2 | METHOD FOR INHIBITING THE REPLICATION OF HERPES VIRUSES | BAYER HEALTHCARE AG (DE) | 2004-07-22 | — | — | WO | disclosed |
| EP-1404657-A1 | PYRIDAZINONE | Bayer HealthCare AG (DE) | 2004-04-07 | — | — | EP | disclosed |
| WO-2003002541-A1 | PYRIDAZINONE | BAYER HEALTHCARE AG (DE) | 2003-01-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050059658-A1 | Pyridazinone | TYMP, TPMT, PDXK | CHRNA1 3542/4885CHRNG 4280/4885CHRNB1 3972/4885 |
| US-20070004735-A1 | Method for inhibiting the replication of herpes viruses | RPL35, PCNA, MCM5 | CHRNA1 4645/4885CHRNG 4660/4885CHRNB1 4733/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.