SCHEMBL5185199

SCHEMBL5185199

Cc1ccc(S(=O)(=O)NC(=O)Nc2cccc(N(S(=O)(=O)c3ccc(C)cc3)S(=O)(=O)c3ccc(C)cc3)c2)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.64
PPARG P37231 1/20 0.58
RAB9A P51151 1/20 0.58
RXFP1 Q9HBX9 1/20 0.58
NR2E3 Q9Y5X4 1/20 0.58
NCOR2 Q9Y618 1/20 0.58
KMT2A Q03164 2/20 0.57
MEN1 O00255 1/20 0.57
CA12 O43570 2/20 0.54
CA9 Q16790 2/20 0.54
TP53 P04637 1/20 0.54
CA1 P00915 1/20 0.54
CA2 P00918 1/20 0.54
CA4 P22748 1/20 0.54
CA6 P23280 1/20 0.54
CA5A P35218 1/20 0.54
CA7 P43166 1/20 0.54
CA13 Q8N1Q1 1/20 0.54
CA14 Q9ULX7 1/20 0.54
KCNA1 Q09470 3/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6241750 0.86 LMNA (0.80) LMNAPPARGRAB9ARXFP1NR2E3
SCHEMBL8970207 0.84 LMNA (0.62) LMNAPPARGRAB9ARXFP1NR2E3
SCHEMBL7514901 0.83 MAPT (0.55) LMNARAB9AKMT2AMEN1CA12
SCHEMBL5184916 0.83 LMNA (0.76) LMNAPPARGRAB9ARXFP1NR2E3
SCHEMBL30343049 0.82 LMNA (0.60) LMNAPPARGRAB9ARXFP1NR2E3
SCHEMBL29445562 0.81 LMNA (0.72) LMNAPPARGRAB9ARXFP1NR2E3
SCHEMBL5184926 0.81 LMNA (0.72) LMNAPPARGRAB9ARXFP1NR2E3
SCHEMBL6465683 0.81 LMNA (0.72) LMNAPPARGRAB9ARXFP1NR2E3
SCHEMBL5185918 0.81 LMNA (0.72) LMNAPPARGRAB9ARXFP1NR2E3
SCHEMBL1395598 0.81 LMNA (0.72) LMNAPPARGRAB9ARXFP1NR2E3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1448397-B1 HEAT-SENSITIVE RECORDING MATERIAL JUJO THERMAL OY (FI) 2007-07-11 EP claimed
US-20050148467-A1 Heat-sensitive recording material JUJO THERMAL OY (FI) 2005-07-07 US claimed
US-20050255998-A1 Mixture of colour developers CIBA SPECIALTY CHEMICALS CORP. 2005-11-17 US disclosed
US-20050106491-A1 Heat sensitive recording material CIBA SPECIALTY CHEMICALS CORP. 2005-05-19 US disclosed
EP-1480835-A1 HEAT SENSITIVE RECORDING MATERIAL Ciba SC Holding AG (CH) 2004-12-01 EP disclosed
WO-2003074285-A1 HEAT SENSITIVE RECORDING MATERIAL CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2003-09-12 WO disclosed