SCHEMBL5185676

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL27892665	0.80	FLT1 (0.46)	FLT1FLT4KDRFAAHSLC22A12
	SCHEMBL27875906	0.80	VCP (0.47)	VCPFLT1FLT4KDRALDH1A1
	SCHEMBL27977306	0.79	PDE4A (0.53)	FLT1FLT4KDRALDH1A1HPGD
	SCHEMBL11707525	0.79	ALOX15 (0.50)	VCPFLT1FLT4KDRALDH1A1
	SCHEMBL2406093	0.78	VCP (0.56)	VCPFLT1FLT4KDRFAAH
	SCHEMBL5472146	0.77	VCP (0.55)	VCPFLT1FLT4KDRFAAH
	SCHEMBL5184574	0.77	VCP (0.55)	VCPFLT1FLT4KDRFAAH
	SCHEMBL5186160	0.77	VCP (0.55)	VCPFLT1FLT4KDRFAAH
	SCHEMBL29243089	0.76	VCP (0.52)	VCPFLT1FLT4KDRFAAH
	SCHEMBL5186180	0.74	VCP (0.53)	VCPFLT1FLT4KDRFAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.