Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 5/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | NSD2 | O96028 | 1/20 | 0.32 |
| ▸ | MMP14 | P50281 | 1/20 | 0.32 |
| ▸ | CASP6 | P55212 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | PTPRC | P08575 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5186210 | 1.00 | PTPN11 (0.36) | PTPN11P2RX3TDP1MEN1KMT2A | |
| SCHEMBL5184472 | 0.99 | PTPN11 (0.37) | PTPN11P2RX3TDP1MEN1KMT2A | |
| SCHEMBL5184478 | 0.99 | PTPN11 (0.37) | PTPN11P2RX3TDP1MEN1KMT2A | |
| SCHEMBL5186206 | 0.90 | THRB (0.34) | PTPN11MEN1KMT2ATHRBPOLB | |
| SCHEMBL5185046 | 0.84 | APEX1 (0.37) | PTPN11MEN1KMT2AALDH1A1THRB | |
| SCHEMBL5185043 | 0.84 | APEX1 (0.37) | PTPN11MEN1KMT2AALDH1A1THRB | |
| SCHEMBL5185545 | 0.84 | MEN1 (0.40) | MEN1KMT2AALDH1A1MAPTMAPK1 | |
| SCHEMBL5185548 | 0.84 | MEN1 (0.40) | MEN1KMT2AALDH1A1MAPTMAPK1 | |
| SCHEMBL5186138 | 0.84 | MEN1 (0.39) | TDP1MEN1KMT2AALDH1A1THRB | |
| SCHEMBL5186132 | 0.84 | MEN1 (0.39) | TDP1MEN1KMT2AALDH1A1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1339700-B1 | PROCESS FOR THE PREPARATION OF BENZOTRIAZOLES | CIBA SC HOLDING AG (CH) | 2007-11-21 | — | — | EP | disclosed |
| US-20070208165-A1 | Process for the preparation of benzotriazoles | FISCHER WALTER | 2007-09-06 | — | — | US | disclosed |
| US-20040019220-A1 | Process for the preparation of benzotriazoles | CIBA SPECIALTY CHEMICALS CORP. | 2004-01-29 | — | — | US | disclosed |
| EP-1339700-A1 | PROCESS FOR THE PREPARATION OF BENZOTRIAZOLES | Ciba SC Holding AG (CH) | 2003-09-03 | — | — | EP | disclosed |
| WO-2002024668-A1 | PROCESS FOR THE PREPARATION OF BENZOTRIAZOLES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2002-03-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070208165-A1 | Process for the preparation of benzotriazoles | CBR1, CCNT1, CYP1B1 | PTPN11 490/4885P2RX3 1121/4885TDP1 1097/4885 |
| US-20040019220-A1 | Process for the preparation of benzotriazoles | SULT1E1, SULT1A1, CYP1B1 | PTPN11 745/4885P2RX3 1442/4885TDP1 1284/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.