Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11702800 | 0.63 | BRD4 (0.34) | — | |
| SCHEMBL19661158 | 0.61 | DYRK1A (0.30) | — | |
| SCHEMBL17224936 | 0.60 | KDM4C (0.40) | CYP2C9MEN1CYP1A2KMT2A | |
| SCHEMBL17224891 | 0.59 | HCAR2 (0.45) | — | |
| SCHEMBL15671015 | 0.58 | CYP17A1 (0.40) | CYP2C19CYP17A1CYP2C9 | |
| SCHEMBL31191115 | 0.57 | CYP2C19 (0.39) | CYP2C19CYP17A1CYP2C9MEN1CYP1A2 | |
| SCHEMBL22100693 | 0.57 | KDM4E (0.30) | — | |
| SCHEMBL27931872 | 0.57 | L3MBTL1 (0.53) | CYP2C19CYP17A1CYP2C9CYP1A2 | |
| SCHEMBL20471503 | 0.56 | — | — | |
| SCHEMBL28013092 | 0.56 | L3MBTL1 (0.40) | CYP2C19MEN1CYP1A2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1789401-A1 | ISOXAZOLINE DERIVATIVES AND THEIR USE AS HERBICIDES | Syngenta Limited (GB) | 2007-05-30 | — | — | EP | disclosed |
| WO-2006024820-A1 | ISOXAZOLINE DERIVATIVES AND THEIR USE AS HERBICIDES | SYNGENTA LIMITED (GB) | 2006-03-09 | — | — | WO | disclosed |