Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19661158 | 0.77 | DYRK1A (0.30) | — | |
| SCHEMBL26942744 | 0.66 | TSHR (0.32) | KDM4EMAPK1 | |
| SCHEMBL12121211 | 0.64 | DYRK1A (0.46) | — | |
| SCHEMBL3465033 | 0.63 | DYRK1A (0.33) | — | |
| SCHEMBL13755079 | 0.62 | P2RX7 (0.33) | KDM4EMAPK1 | |
| SCHEMBL3402634 | 0.61 | DYRK1A (0.32) | — | |
| SCHEMBL3464724 | 0.61 | L3MBTL1 (0.39) | — | |
| SCHEMBL2875793 | 0.61 | ALOX15 (0.34) | — | |
| SCHEMBL4241088 | 0.61 | — | — | |
| SCHEMBL13748111 | 0.60 | DYRK1A (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200190059-A1 | SULFONYL PIPERIDINE DERIVATIVES AND THEIR USE FOR TREATING PROKINETICIN MEDIATED DISEASES | TAKEDA PHARMACEUTICALS CO (JP) | 2020-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200190059-A1 | SULFONYL PIPERIDINE DERIVATIVES AND THEIR USE FOR TREATING PROKINETICIN MEDIATED DISEASES | PROKR1, GIPR, PROKR2 | KDM4E 4135/4885MAPK1 1850/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.