Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | FBP1 | P09467 | 11/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | HTR2A | P28223 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | PPARA | Q07869 | 2/20 | 0.49 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5937515 | 0.89 | FBP1 (0.50) | TDP1FBP1TSHRHTR2ACYP1A2 | |
| SCHEMBL5186662 | 0.84 | FBP1 (0.53) | FBP1TSHRHTR2ACYP1A2PPARA | |
| SCHEMBL5186651 | 0.81 | PORCN (0.46) | TDP1FBP1TSHRCYP1A2CYP3A4 | |
| SCHEMBL5186608 | 0.81 | FBP1 (0.52) | FBP1TSHRHTR2ACYP1A2PPARA | |
| SCHEMBL5186641 | 0.81 | FBP1 (0.52) | FBP1TSHRHTR2ACYP1A2PPARA | |
| SCHEMBL4113937 | 0.81 | FBP1 (0.54) | FBP1TSHRHTR2ACYP1A2PPARA | |
| SCHEMBL5186614 | 0.79 | FBP1 (0.53) | FBP1TSHRHTR2ACYP1A2PPARA | |
| SCHEMBL5186652 | 0.78 | FBP1 (0.54) | FBP1TSHRHTR2ACYP1A2PPARA | |
| SCHEMBL1549824 | 0.77 | FBP1 (0.58) | TDP1FBP1TSHRHTR2ACYP1A2 | |
| SCHEMBL5188822 | 0.77 | FBP1 (0.53) | FBP1TSHRHTR2ACYP1A2PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1863772-A1 | AMIDE DERIVATIVES AS PPAR ACTIVATORS | F.HOFFMANN-LA ROCHE AG (CH) | 2007-12-12 | — | — | EP | disclosed |
| WO-2007028424-A1 | AMIDE DERIVATIVES AS PPAR ACTIVATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2007-03-15 | — | — | WO | disclosed |
| US-20060183754-A1 | Amide bridged piphenyl or biazaphenyl derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 2006-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060183754-A1 | Amide bridged piphenyl or biazaphenyl derivatives | PPARD, PPARA, PPARG | TDP1 4308/4885FBP1 1713/4885TSHR 226/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.