Propylene Oxide

Propylene Oxide

SCHEMBL5187461

C=C(C)C(=O)OCC(C)O.CC1CO1

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.55
ALDH1A1 P00352 2/20 0.53
THRB P10828 1/20 0.36
MAPT P10636 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL27509874 0.95 TSHR (0.50) TSHRALDH1A1THRBMAPT
SCHEMBL4627030 0.86 ALDH1A1 (0.76) TSHRALDH1A1THRB
SCHEMBL19017 0.86 TSHR (0.72) TSHRALDH1A1THRBMAPT
SCHEMBL9695772 0.86 TSHR (0.72) TSHRALDH1A1THRBMAPT
SCHEMBL4866878 0.84 ALDH1A1 (0.64) TSHRALDH1A1THRBMAPT
Propylene Oxide SCHEMBL9651632 0.84 TSHR (0.56) TSHRALDH1A1THRB
Propylene Oxide SCHEMBL14648044 0.84 ALDH1A1 (0.50) TSHRALDH1A1THRB
Hydrochloric Acid SCHEMBL27495672 0.84 TSHR (0.69) TSHRALDH1A1THRBMAPT
Ammonia Solution, Strong SCHEMBL28645738 0.84 TSHR (0.69) TSHRALDH1A1THRBMAPT
Isobutane SCHEMBL28146334 0.84 TSHR (0.69) TSHRALDH1A1THRBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1177830-B1 Reaction method using heterogeneous catalyst and reaction apparatus therefor NIPPON CATALYTIC CHEM IND (JP) 2007-07-18 EP disclosed
EP-1177830-A2 Reaction method using heterogeneous catalyst and reaction apparatus therefor Nippon Shokubai Co., Ltd. (JP) 2002-02-06 EP disclosed
US-5232816-A Resists coatings for printed circuit boards NIPPON PAINT CO., LTD. (JP) 1993-08-03 US disclosed
EP-0416829-A2 A positive type photosensitive resinous composition NIPPON PAINT CO., LTD. (JP) 1991-03-13 EP disclosed