SCHEMBL518802

SCHEMBL518802

CCCCCCCCC=CCCCCCCCCCCCCNCCCCCCCCCCCCC=CCCCCCCCC

nearest known ligand 0.65

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.65
ALDH1A1 P00352 1/20 0.65
FAAH O00519 2/20 0.62
TRPV1 Q8NER1 2/20 0.62
PPARA Q07869 2/20 0.57
EPHX1 P07099 1/20 0.52
ADH1B P00325 1/20 0.52
ADH1C P00326 1/20 0.52
ADH1A P07327 1/20 0.52
ADH4 P08319 1/20 0.52
ADH7 P40394 1/20 0.52
EPHX2 P34913 6/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9480001 1.00 TSHR (0.65) TSHRALDH1A1FAAHTRPV1PPARA
SCHEMBL9208641 1.00 TSHR (0.65) TSHRALDH1A1FAAHTRPV1PPARA
SCHEMBL6677501 1.00 TSHR (0.65) TSHRALDH1A1FAAHTRPV1PPARA
SCHEMBL519455 1.00 TSHR (0.65) TSHRALDH1A1FAAHTRPV1PPARA
SCHEMBL11786437 1.00 TSHR (0.65) TSHRALDH1A1FAAHTRPV1PPARA
SCHEMBL23117202 1.00 TSHR (0.65) TSHRALDH1A1FAAHTRPV1PPARA
SCHEMBL518800 1.00 TSHR (0.65) TSHRALDH1A1FAAHTRPV1PPARA
SCHEMBL554166 1.00 TSHR (0.65) TSHRALDH1A1FAAHTRPV1PPARA
SCHEMBL22063916 1.00 TSHR (0.65) TSHRALDH1A1FAAHTRPV1PPARA
SCHEMBL296807 1.00 TSHR (0.65) TSHRALDH1A1FAAHTRPV1PPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9226925-B1 Abuse deterrent and anti-dose dumping pharmaceutical salts useful for the treatment of attention deficit/hyperactivity disorder PISGAH LABORATORIES, INC. (US) 2016-01-05 US claimed
US-8940729-B1 Abuse deterrent and anti-dose dumping pharmaceutical salts useful for the treatment of attention deficit/hyperactivity disorder PISGAH LABORATORIES, INC. (US) 2015-01-27 US claimed
US-8912217-B1 Abuse deterrent and anti-dose dumping pharmaceutical salts useful for the treatment of attention deficit/hyperactivity disorder PISGAH LABORATORIES, INC. (US) 2014-12-16 US claimed
EP-0149601-B1 SLIP AND BLOCK ADDITIVES FOR OLEFIN POLYMERS THE DOW CHEMICAL COMPANY (US) 1990-07-04 EP claimed
EP-0149601-A4 SLIP AND BLOCK ADDITIVES FOR OLEFIN POLYMERS. DOW CHEMICAL CO (US) 1985-11-21 EP claimed
EP-0149601-A1 SLIP AND BLOCK ADDITIVES FOR OLEFIN POLYMERS. DOW CHEMICAL CO (US) 1985-07-31 EP claimed
WO-1985000613-A1 SLIP AND BLOCK ADDITIVES FOR OLEFIN POLYMERS THE DOW CHEMICAL COMPANY (US) 1985-02-14 WO claimed
US-4394474-A MINERAL, SECONDARY FATTY AMIDE THE DOW CHEMICAL COMPANY (US) 1983-07-19 US claimed
US-9226925-B1 Abuse deterrent and anti-dose dumping pharmaceutical salts useful for the treatment of attention deficit/hyperactivity disorder PISGAH LABORATORIES, INC. (US) 2016-01-05 US disclosed
US-8980880-B1 Abuse deterrent and anti-dose dumping pharmaceutical salts useful for the treatment of attention deficit/hyperactivity disorder PISGAH LABORATORIES, INC. (US) 2015-03-17 US disclosed
US-8957067-B1 Abuse deterrent and anti-dose dumping pharmaceutical salts useful for the treatment of attention deficit/hyperactivity disorder PISGAH LABORATORIES, INC. (US) 2015-02-17 US disclosed
US-8940729-B1 Abuse deterrent and anti-dose dumping pharmaceutical salts useful for the treatment of attention deficit/hyperactivity disorder PISGAH LABORATORIES, INC. (US) 2015-01-27 US disclosed
US-8916587-B1 Abuse deterrent and anti-dose dumping pharmaceutical salts useful for the treatment of attention deficit/hyperactivity disorder PISGAH LABORATORIES, INC. (US) 2014-12-23 US disclosed
US-8912217-B1 Abuse deterrent and anti-dose dumping pharmaceutical salts useful for the treatment of attention deficit/hyperactivity disorder PISGAH LABORATORIES, INC. (US) 2014-12-16 US disclosed
US-4795767-A POLYETHYLENE BLEND WITH MINERAL FILLER, SECONDARY AMIDE, ANTIOXIDANT AND PHOSPHORUS COMPOUND UNION CARBIDE CORPORATION (US) 1989-01-03 US disclosed
EP-0149601-A4 SLIP AND BLOCK ADDITIVES FOR OLEFIN POLYMERS. DOW CHEMICAL CO (US) 1985-11-21 EP disclosed
EP-0149601-A1 SLIP AND BLOCK ADDITIVES FOR OLEFIN POLYMERS. DOW CHEMICAL CO (US) 1985-07-31 EP disclosed
WO-1985000613-A1 SLIP AND BLOCK ADDITIVES FOR OLEFIN POLYMERS THE DOW CHEMICAL COMPANY (US) 1985-02-14 WO disclosed
US-4454272-A SECONDARY AMIDE, MINERAL, ETHYLENE COPOLYMER THE DOW CHEMICAL COMPANY (US) 1984-06-12 US disclosed
US-4394474-A MINERAL, SECONDARY FATTY AMIDE THE DOW CHEMICAL COMPANY (US) 1983-07-19 US disclosed