SCHEMBL554166

SCHEMBL554166

CCCCCCCCC=CCCCCCCCCNCCCCCCCCC=CCCCCCCCC

nearest known ligand 0.65

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.65
ALDH1A1 P00352 1/20 0.65
FAAH O00519 2/20 0.62
TRPV1 Q8NER1 2/20 0.62
PPARA Q07869 2/20 0.57
EPHX1 P07099 1/20 0.52
ADH1B P00325 1/20 0.52
ADH1C P00326 1/20 0.52
ADH1A P07327 1/20 0.52
ADH4 P08319 1/20 0.52
ADH7 P40394 1/20 0.52
EPHX2 P34913 6/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9480001 1.00 TSHR (0.65) TSHRALDH1A1FAAHTRPV1PPARA
SCHEMBL518802 1.00 TSHR (0.65) TSHRALDH1A1FAAHTRPV1PPARA
SCHEMBL9208641 1.00 TSHR (0.65) TSHRALDH1A1FAAHTRPV1PPARA
SCHEMBL6677501 1.00 TSHR (0.65) TSHRALDH1A1FAAHTRPV1PPARA
SCHEMBL519455 1.00 TSHR (0.65) TSHRALDH1A1FAAHTRPV1PPARA
SCHEMBL11786437 1.00 TSHR (0.65) TSHRALDH1A1FAAHTRPV1PPARA
SCHEMBL23117202 1.00 TSHR (0.65) TSHRALDH1A1FAAHTRPV1PPARA
SCHEMBL518800 1.00 TSHR (0.65) TSHRALDH1A1FAAHTRPV1PPARA
SCHEMBL22063916 1.00 TSHR (0.65) TSHRALDH1A1FAAHTRPV1PPARA
SCHEMBL296807 1.00 TSHR (0.65) TSHRALDH1A1FAAHTRPV1PPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 110 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009020430-A2 METHOD OF FORMING A CADMIUM CONTAINING NANOCRYSTAL AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2009-02-12 WO claimed
EP-1513638-B1 METAL POWDER COMPOSITION INCLUDING A BONDING LUBRICANT AND A BONDING LUBRICANT COMPRISING GLYCERYL STEARATE. HOEGANAES AB (SE) 2008-08-20 EP claimed
US-20080090742-A1 Compound and method of making the compound AFTON CHEMICAL CORPORATION 2008-04-17 US claimed
EP-0960224-B1 SPANDEX WITH LOW TACKINESS AND PROCESS FOR MAKING SAME DU PONT (US) 2001-12-12 EP claimed
US-6268534-B1 CONTACTING OLEYL BROMIDE WITH OLEYLAMINE UNDER CONDITIONS SUITABLE FOR THE FORMATION OF N,N-DIOLEYLAMINE; METHYLATION OF N,N-DIOLEYLAMINE UNDER CONDITIONS SUITABLE FOR FORMATION OF N,N-DIOLEYL-N,N-DIMETHYLAMMONIUM CHLORIDE RIBOZYME PHARMACEUTICALS, INC. 2001-07-31 US claimed
EP-3262147-B1 AROMATIC DETERGENTS AND LUBRICATING COMPOSITIONS THEREOF LUBRIZOL CORP (US) 2025-01-22 EP disclosed
EP-3390591-B1 LUBRICATING COMPOSITIONS COMPRISING SULFURIZED CATECHOLATE DETERGENTS LUBRIZOL CORP (US) 2024-10-30 EP disclosed
US-11633365-B2 Nucleic acid-containing lipid nanoparticle KYOWA KIRIN CO., LTD. (JP) 2023-04-25 US disclosed
EP-3209756-B1 DISPERSANT VISCOSITY MODIFIERS WITH SULFONATE FUNCTIONALITY LUBRIZOL CORP (US) 2022-11-02 EP disclosed
US-11149226-B2 Preparation and use of aminoalkylphosphonic acid dialkyl ester compounds in a lubricant for antiwear, friction reduction, and/or micropitting prevention AFTON CHEMICAL CORPORATION (US) 2021-10-19 US disclosed
US-20210309932-A1 Lubricating Compositions THE LUBRIZOL CORPORATION (US) 2021-10-07 US disclosed
EP-3480256-B1 POLYAMIDE RESIN MOLDED ARTICLE ASAHI CHEMICAL IND (JP) 2021-05-05 EP disclosed
EP-0519760-A1 Oil additive concentrates and lubricants of enhanced performance capabilities ETHYL PETROLEUM ADDITIVES, INC. (US) 1992-12-23 EP disclosed
US-4941983-A Fluid loss-reducing additives for oil-based well working fluids SANDOZ LTD. (CH) 1990-07-17 US disclosed
EP-0259266-A2 Improvements in or relating to organic compounds SANDOZ AG (CH) 1988-03-09 EP disclosed
EP-0049484-B1 A PROCESS FOR THE PRODUCTION OF A FLUID LOSS REDUCING ADDITIVE FOR AN OIL-BASED WELL WORKING FLUID B W MUD LIMITED (GB) 1984-12-19 EP disclosed
US-4371446-A COMPOSED OF DUOMEEN-T-DIOLEATE AND A DIAMIDE NIPPN OIL COMPANY, LTD. (JP) 1983-02-01 US disclosed
EP-0049484-A1 A process for the production of a fluid loss reducing additive for an oil-based well working fluid B W MUD LIMITED (GB) 1982-04-14 EP disclosed
US-3995059-A CHOLESTEROL LOWERING AGENTS SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1976-11-30 US disclosed
US-3960613-A Wax-flux composition containing amine salts of carboxylic acids for soldering CHEVRON RESEARCH COMPANY (US) 1976-06-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11633365-B2 Nucleic acid-containing lipid nanoparticle LIPA, LIPC, PNLIP TSHR 3238/4885ALDH1A1 354/4885FAAH 89/4885
US-11149226-B2 Preparation and use of aminoalkylphosphonic acid dialkyl ester compounds in a lubricant for antiwear, friction reduction, and/or micropitting prevention TP53RK, PHOSPHO1, PTAFR TSHR 2938/4885ALDH1A1 3134/4885FAAH 1898/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.