SCHEMBL519455

SCHEMBL519455

CCCCCC/C=C\CCCCCCCCNCCCCCCCC/C=C\CCCCCC

nearest known ligand 0.65

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.65
ALDH1A1 P00352 1/20 0.65
FAAH O00519 2/20 0.62
TRPV1 Q8NER1 2/20 0.62
PPARA Q07869 2/20 0.57
EPHX1 P07099 1/20 0.52
ADH1B P00325 1/20 0.52
ADH1C P00326 1/20 0.52
ADH1A P07327 1/20 0.52
ADH4 P08319 1/20 0.52
ADH7 P40394 1/20 0.52
EPHX2 P34913 6/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9480001 1.00 TSHR (0.65) TSHRALDH1A1FAAHTRPV1PPARA
SCHEMBL518802 1.00 TSHR (0.65) TSHRALDH1A1FAAHTRPV1PPARA
SCHEMBL9208641 1.00 TSHR (0.65) TSHRALDH1A1FAAHTRPV1PPARA
SCHEMBL6677501 1.00 TSHR (0.65) TSHRALDH1A1FAAHTRPV1PPARA
SCHEMBL11786437 1.00 TSHR (0.65) TSHRALDH1A1FAAHTRPV1PPARA
SCHEMBL23117202 1.00 TSHR (0.65) TSHRALDH1A1FAAHTRPV1PPARA
SCHEMBL518800 1.00 TSHR (0.65) TSHRALDH1A1FAAHTRPV1PPARA
SCHEMBL554166 1.00 TSHR (0.65) TSHRALDH1A1FAAHTRPV1PPARA
SCHEMBL22063916 1.00 TSHR (0.65) TSHRALDH1A1FAAHTRPV1PPARA
SCHEMBL296807 1.00 TSHR (0.65) TSHRALDH1A1FAAHTRPV1PPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9226925-B1 Abuse deterrent and anti-dose dumping pharmaceutical salts useful for the treatment of attention deficit/hyperactivity disorder PISGAH LABORATORIES, INC. (US) 2016-01-05 US claimed
US-8940729-B1 Abuse deterrent and anti-dose dumping pharmaceutical salts useful for the treatment of attention deficit/hyperactivity disorder PISGAH LABORATORIES, INC. (US) 2015-01-27 US claimed
US-8912217-B1 Abuse deterrent and anti-dose dumping pharmaceutical salts useful for the treatment of attention deficit/hyperactivity disorder PISGAH LABORATORIES, INC. (US) 2014-12-16 US claimed
WO-2025028468-A1 HYDROPHILICITY-IMPARTING AGENT AND RESIN COMPOSITION CONTAINING SAME 日油株式会社 2025-02-06 WO disclosed
EP-2871178-B1 CATIONIC LIPID KYOWA KIRIN CO LTD (JP) 2020-12-23 EP disclosed
US-10342758-B2 Cationic lipid KYOWA HAKKO KIRIN CO., LTD. (JP) 2019-07-09 US disclosed
US-10342758-B2 Cationic lipid KYOWA HAKKO KIRIN CO., LTD. (JP) 2019-07-09 US disclosed
EP-3275448-A1 NUCLEIC ACID-CONTAINING LIPID NANOPARTICLES Kyowa Hakko Kirin Co., Ltd. (JP) 2018-01-31 EP disclosed
US-9226925-B1 Abuse deterrent and anti-dose dumping pharmaceutical salts useful for the treatment of attention deficit/hyperactivity disorder PISGAH LABORATORIES, INC. (US) 2016-01-05 US disclosed
US-20150174261-A1 CATIONIC LIPID KYOWA KIRIN CO., LTD. (JP) 2015-06-25 US disclosed
US-20150174261-A1 CATIONIC LIPID KYOWA KIRIN CO., LTD. (JP) 2015-06-25 US disclosed
US-8846766-B2 Abuse-deterrent methadone for the safe treatment of drug abuse and pain relief PISGAH LABORATORIES, INC. (US) 2014-09-30 US disclosed
US-8716278-B1 Abuse deterrent and anti-dose dumping pharmaceutical salts useful for the treatment of attention deficit/hyperactivity disorder PISGAH LABORATORIES, INC. (US) 2014-05-06 US disclosed
US-8716337-B1 Abuse deterrent and anti-dose dumping pharmaceutical salts useful for the treatment of attention deficit/hyperactivity disorder PISGAH LABORATORIES, INC. (US) 2014-05-06 US disclosed
US-8653065-B1 Abuse deterrent and anti-dose dumping pharmaceutical salts useful for the treatment of attention deficit/hyperactivity disorder PISGAH LABORATORIES, INC. (US) 2014-02-18 US disclosed
US-8653106-B2 Abuse deterrent and anti-dose dumping pharmaceutical salts useful for the treatment of attention deficit/hyperactivity disorder PISGAH LABORATORIES, INC. (US) 2014-02-18 US disclosed
WO-2014007398-A1 CATIONIC LIPID 協和発酵キリン株式会社 (JP) 2014-01-09 WO disclosed
US-20130338229-A1 Abuse-Deterrent Methadone for the Safe Treatment of Drug Abuse and Pain Relief Pisgah National Laboratories, Inc. (US) 2013-12-19 US disclosed
US-8586575-B1 Abuse deterrent and anti-dose dumping pharmaceutical salts useful for the treatment of attention deficit/hyperactivity disorder PISGAH LABORATORIES, INC. (US) 2013-11-19 US disclosed
US-20120028960-A1 ABUSE DETERRENT AND ANTI-DOSE DUMPING PHARMACEUTICAL SALTS USEFUL FOR THE TREATMENT OF ATTENTION DEFICIT/HYPERACTIVITY DISORDER PISGAH LABORATORIES, INC. 2012-02-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130338229-A1 Abuse-Deterrent Methadone for the Safe Treatment of Drug Abuse and Pain Relief OPRM1, OGFR, OPRK1 TSHR 2195/4885ALDH1A1 469/4885FAAH 1334/4885
US-10342758-B2 Cationic lipid LIPA, LCLAT1, RNASEH1 TSHR 1013/4885ALDH1A1 3766/4885FAAH 969/4885
US-20120028960-A1 ABUSE DETERRENT AND ANTI-DOSE DUMPING PHARMACEUTICAL SALTS USEFUL FOR THE TREATMENT OF ATTENTION DEFICIT/HYPERACTIVITY DISORDER COMT, SLC6A3, SLC6A2 TSHR 2160/4885ALDH1A1 235/4885FAAH 676/4885
US-20150174261-A1 CATIONIC LIPID LIPA, LCLAT1, RNASEH1 TSHR 1013/4885ALDH1A1 3766/4885FAAH 969/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.