Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 8/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | PPARD | Q03181 | 3/20 | 0.42 |
| ▸ | PPARA | Q07869 | 3/20 | 0.42 |
| ▸ | CETP | P11597 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.41 |
| ▸ | FBP1 | P09467 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5188253 | 0.92 | FFAR4 (0.45) | HDAC1HDAC2MAPTTP53PPARD | |
| SCHEMBL5186637 | 0.90 | PPARA (0.53) | MCHR1PPARDPPARAFFAR4PPARG | |
| SCHEMBL5188244 | 0.85 | PPARA (0.41) | MCHR1PPARDPPARAFFAR4PPARG | |
| SCHEMBL5187722 | 0.82 | PPARA (0.49) | MCHR1MAPTTP53PPARDPPARA | |
| SCHEMBL5187778 | 0.82 | FFAR4 (0.49) | PPARDPPARAFFAR4PPARG | |
| SCHEMBL5188254 | 0.82 | IDH1 (0.42) | MCHR1MAPTTP53FBP1 | |
| SCHEMBL5188293 | 0.81 | PPARD (0.47) | MAPTTP53PPARDPPARAPPARG | |
| SCHEMBL5186708 | 0.80 | PPARD (0.39) | MCHR1MAPTTP53PPARDPPARA | |
| SCHEMBL5188800 | 0.80 | PSEN1 (0.46) | MCHR1MAPTPPARDPPARAPPARG | |
| SCHEMBL5648539 | 0.79 | PPARA (0.48) | PPARDPPARAPPARGFBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1863772-A1 | AMIDE DERIVATIVES AS PPAR ACTIVATORS | F.HOFFMANN-LA ROCHE AG (CH) | 2007-12-12 | — | — | EP | disclosed |
| WO-2007028424-A1 | AMIDE DERIVATIVES AS PPAR ACTIVATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2007-03-15 | — | — | WO | disclosed |