Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
| ▸ | CTSD | P07339 | 1/20 | 0.33 |
| ▸ | DGKA | P23743 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.32 |
| ▸ | GABRP | O00591 | 2/20 | 0.32 |
| ▸ | GABRD | O14764 | 2/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9619793 | 1.00 | ALDH1A1 (0.58) | ALDH1A1MAPTLMNACES2CES1 | |
| SCHEMBL542251 | 0.89 | ALDH1A1 (0.40) | ALDH1A1MAPTLMNACYP1A2GABRP | |
| SCHEMBL15657907 | 0.89 | ALDH1A1 (0.40) | ALDH1A1MAPTLMNACYP1A2GABRP | |
| SCHEMBL3284598 | 0.84 | LMNA (0.56) | ALDH1A1MAPTLMNANAAADGKA | |
| SCHEMBL898141 | 0.84 | LMNA (0.56) | ALDH1A1MAPTLMNANAAADGKA | |
| SCHEMBL9666107 | 0.84 | LMNA (0.56) | ALDH1A1MAPTLMNANAAADGKA | |
| SCHEMBL15649885 | 0.84 | LMNA (0.56) | ALDH1A1MAPTLMNANAAADGKA | |
| SCHEMBL15689282 | 0.84 | LMNA (0.56) | ALDH1A1MAPTLMNANAAADGKA | |
| SCHEMBL17204169 | 0.84 | LMNA (0.56) | ALDH1A1MAPTLMNANAAADGKA | |
| SCHEMBL29043323 | 0.84 | LMNA (0.56) | ALDH1A1MAPTLMNANAAADGKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1859029-A2 | ACIDOPHILIC ENZYMES | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2007-11-28 | — | — | EP | disclosed |
| WO-2006094943-A2 | ACIDOPHILIC ENZYMES | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2006-09-14 | — | — | WO | disclosed |