Known targets — ChEMBL curated mechanism
CHRM1DRD2DRD3DRD4HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR2APDE3ASIGMAR1
The experimentally established mechanism targets of Lactic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.66 |
| ▸ | MEN1 | O00255 | 1/20 | 0.66 |
| ▸ | THRB | P10828 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 1/20 | 0.66 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | CES2 | O00748 | 2/20 | 0.47 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.44 |
| ▸ | PLA2G2C | Q5R387 | 2/20 | 0.43 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lactic Acid SCHEMBL27991357 | 0.93 | CES2 (0.53) | HTTMEN1THRBKMT2AMAPT | |
| Lactic Acid SCHEMBL27962244 | 0.93 | CES2 (0.53) | HTTMEN1THRBKMT2AMAPT | |
| Isopropyl Alcohol SCHEMBL10959119 | 0.85 | MEN1 (0.83) | HTTMEN1THRBKMT2AMAPT | |
| Di(Hydroxyethyl)Ether SCHEMBL28174751 | 0.84 | TP53 (0.55) | HTTMEN1THRBKMT2AMAPT | |
| Lactic Acid SCHEMBL3626494 | 0.84 | HTT (0.50) | HTTMEN1THRBKMT2AMAPT | |
| Propylene Glycol SCHEMBL5711852 | 0.83 | MEN1 (0.73) | HTTMEN1THRBKMT2AMAPT | |
| Triethylene Glycol SCHEMBL19064978 | 0.83 | MEN1 (0.80) | HTTMEN1THRBKMT2AMAPT | |
| Lactic Acid SCHEMBL8443690 | 0.83 | GAA (0.46) | HTTMEN1THRBKMT2AMAPT | |
| Acetic Acid SCHEMBL28282561 | 0.83 | MEN1 (0.72) | HTTMEN1THRBKMT2AMAPT | |
| Di(Hydroxyethyl)Ether SCHEMBL23356787 | 0.82 | MEN1 (0.95) | HTTMEN1THRBKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1806969-A1 | INSECT REPELLENT COMPOSITIONS COMPRISING DIHYDRONEPETALACTONE, AN ALCOHOL, AND AN ESTER | E.I.Du pont de nemours and company (US) | 2007-07-18 | — | — | EP | disclosed |
| WO-2006050519-A1 | INSECT REPELLENT COMPOSITIONS COMPRISING DIHYDRONEPETALACTONE, AN ALCOHOL, AND AN ESTER | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2006-05-11 | — | — | WO | disclosed |