SCHEMBL5189679

SCHEMBL5189679

CC1=Cc2c(-c3ccccc3)cccc2C1[Hf](C)(C)(C1C(C)=Cc2c(-c3ccccc3)cccc21)[SiH](C)c1ccccc1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CHRNB2 P17787 1/20 0.31
CHRNA4 P43681 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1045934 0.88 BRD4 (0.31) CHRNB2CHRNA4
SCHEMBL218389 0.86
SCHEMBL5188332 0.85
SCHEMBL797048 0.80
Hydrochloric Acid SCHEMBL6438059 0.79 BRD4 (0.33) CHRNB2CHRNA4
SCHEMBL8204144 0.79 BRD4 (0.33) CHRNB2CHRNA4
SCHEMBL218568 0.79
SCHEMBL217396 0.78 HTR2B (0.31)
SCHEMBL1051057 0.78 NPC1 (0.30)
Hydrochloric Acid SCHEMBL7926992 0.78 BRD4 (0.32) CHRNB2CHRNA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6410665-B1 POLYMERIZATION COORDINATION CATALYST FOR ALPHA-OLEFIN BASELL POLYOLEFINE GMBH (DE) 2002-06-25 US claimed
EP-0824113-B2 Supported catalyst, process for its preparation and its use in olefin polymerization BASELL POLYOLEFINE GMBH (DE) 2012-06-27 EP disclosed
EP-0811627-B1 Neutral or ionic compound suitable as catalyst component for olefin polymerization BASELL POLYOLEFINE GMBH (DE) 2007-07-25 EP disclosed
EP-0824112-B1 Supported chemical compound BASELL POLYOLEFINE GMBH (DE) 2006-05-10 EP disclosed
US-6410665-B1 POLYMERIZATION COORDINATION CATALYST FOR ALPHA-OLEFIN BASELL POLYOLEFINE GMBH (DE) 2002-06-25 US disclosed
EP-0824113-B1 Supported catalyst, process for its preparation and its use in olefin polymerization BASELL POLYOLEFINE GMBH (DE) 2001-06-20 EP disclosed
EP-0824112-A1 Supported chemical compound HOECHST AKTIENGESELLSCHAFT (DE) 1998-02-18 EP disclosed
EP-0824113-A1 Supported catalyst, process for its preparation and its use in olefin polymerization HOECHST AKTIENGESELLSCHAFT (DE) 1998-02-18 EP disclosed
EP-0811627-A2 Neutral or ionic compound suitable as catalyst component for olefin polymerization HOECHST AKTIENGESELLSCHAFT (DE) 1997-12-10 EP disclosed