SCHEMBL1045934

SCHEMBL1045934

CC1=Cc2c(-c3ccccc3)cccc2C1[Hf](C)(C)(C1C(C)=Cc2c(-c3ccccc3)cccc21)[SiH](C)C

nearest known ligand 0.31

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 1/20 0.31
PDCD1 Q15116 1/20 0.31
CD274 Q9NZQ7 1/20 0.31
USP30 Q70CQ3 1/20 0.30
CHRNB2 P17787 1/20 0.30
CHRNA4 P43681 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1051057 0.90 NPC1 (0.30)
SCHEMBL5189679 0.88 CHRNB2 (0.31) CHRNB2CHRNA4
SCHEMBL1050998 0.86 HTR7 (0.31)
SCHEMBL1051406 0.85 NR1H4 (0.32) BRD4
SCHEMBL217396 0.84 HTR2B (0.31) BRD4PDCD1CD274
Hydrochloric Acid SCHEMBL6438059 0.82 BRD4 (0.33) BRD4PDCD1CD274USP30CHRNB2
SCHEMBL8204144 0.82 BRD4 (0.33) BRD4PDCD1CD274USP30CHRNB2
SCHEMBL1048785 0.82 KDM4E (0.32)
SCHEMBL22301298 0.82
Hydrochloric Acid SCHEMBL7926992 0.81 BRD4 (0.32) BRD4PDCD1CD274USP30CHRNB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10676547-B2 Aluminum alkyls with pendant olefins on clays EXXONMOBIL CHEMICAL PATENTS INC. (US) 2020-06-09 US claimed
US-20180201700-A1 Aluminum Alkyls with Pendant Olefins on Clays EXXONMOBIL CHEMICAL PATENTS INC. 2018-07-19 US claimed
EP-3344385-A1 ALUMINUM ALKYLS WITH PENDANT OLEFINS ON CLAYS ExxonMobil Chemical Patents Inc. (US) 2018-07-11 EP claimed
WO-2017039994-A1 ALUMINUM ALKYLS WITH PENDANT OLEFINS ON CLAYS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2017-03-09 WO claimed
US-20120178617-A1 Preparation of Supported Silyl-Capped Silica-Bound Anion Activators and Associated Catalysts EXXONMOBIL CHEMICAL PATENTS INC. 2012-07-12 US claimed
US-8163854-B2 Preparation of supported silyl-capped silica-bound anion activators and associated catalysts EXXONMOBIL CHEMICAL PATENTS INC. (US) 2012-04-24 US claimed
EP-1799726-B1 TRIALKYLALUMINUM TREATED SUPPORTS EXXONMOBIL CHEM PATENTS INC (US) 2011-07-13 EP claimed
US-20110015357-A1 Preparation of Supported Silyl-Capped Silica-Bound Anion Activators and Associated Catalysts EXXONMOBIL CHEMICAL PATENTS INC. 2011-01-20 US claimed
US-7741417-B2 Preparation of polymerization catalyst activators utilizing indole-modified silica supports EXXONMOBIL CHEMICAL PATENTS INC. (US) 2010-06-22 US claimed
US-7385015-B2 Trialkylaluminum treated supports EXXONMOBIL CHEMICAL PATENTS INC. (US) 2008-06-10 US claimed
US-20070055028-A1 Preparation of polymerization catalyst activators utilizing indole-modified silica supports EXXONMOBIL CHEMICAL PATENTS INC. 2007-03-08 US claimed
US-20060079394-A1 Trialkylaluminum treated supports EXXONMOBIL CHEMICAL PATENTS INC. 2006-04-13 US claimed
US-20050148743-A1 polymerization catalyst systems comprising an ion-exchange layered silicate, an organoaluminum compound, and a heterocyclic compound EXXONMOBIL CHEMICAL PATENTS INC. 2005-07-07 US claimed
US-11708434-B2 Silica quenching agents for use in polymerization process EXXONMOBIL CHEMICAL PATENTS INC. (US) 2023-07-25 US disclosed
US-11142593-B2 Lecithin quenching agent EXXONMOBIL CHEMICAL PATENTS INC. (US) 2021-10-12 US disclosed
US-20210277154-A1 Silica Quenching Agents for use in Polymerization Process EXXONMOBIL CHEMICAL PATENTS INC (US) 2021-09-09 US disclosed
US-7220695-B2 Supported activator EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-05-22 US disclosed
US-20070055028-A1 Preparation of polymerization catalyst activators utilizing indole-modified silica supports EXXONMOBIL CHEMICAL PATENTS INC. 2007-03-08 US disclosed
US-20060079394-A1 Trialkylaluminum treated supports EXXONMOBIL CHEMICAL PATENTS INC. 2006-04-13 US disclosed
US-20050148743-A1 polymerization catalyst systems comprising an ion-exchange layered silicate, an organoaluminum compound, and a heterocyclic compound EXXONMOBIL CHEMICAL PATENTS INC. 2005-07-07 US disclosed