SCHEMBL217396

SCHEMBL217396

CC1=Cc2c(-c3ccccc3)cccc2C1[Hf](Cl)(Cl)(C1C(C)=Cc2c(-c3ccccc3)cccc21)[SiH](C)C

nearest known ligand 0.31

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
HTR2B P41595 2/20 0.31
TMEM97 Q5BJF2 2/20 0.31
HTR1A P08908 1/20 0.31
HTR7 P34969 1/20 0.31
SIGMAR1 Q99720 1/20 0.31
BRD4 O60885 1/20 0.31
PDCD1 Q15116 1/20 0.30
CD274 Q9NZQ7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1120691 0.91
SCHEMBL2233744 0.90
SCHEMBL218389 0.88
SCHEMBL218568 0.86
SCHEMBL817868 0.86
SCHEMBL8361401 0.86
SCHEMBL2236542 0.86 HTR7 (0.31) HTR7
SCHEMBL818247 0.86 NR1H4 (0.31) BRD4
SCHEMBL7182157 0.86
SCHEMBL818182 0.85 JAK2 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 190 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10676547-B2 Aluminum alkyls with pendant olefins on clays EXXONMOBIL CHEMICAL PATENTS INC. (US) 2020-06-09 US claimed
US-20180201700-A1 Aluminum Alkyls with Pendant Olefins on Clays EXXONMOBIL CHEMICAL PATENTS INC. 2018-07-19 US claimed
EP-3344385-A1 ALUMINUM ALKYLS WITH PENDANT OLEFINS ON CLAYS ExxonMobil Chemical Patents Inc. (US) 2018-07-11 EP claimed
WO-2017039994-A1 ALUMINUM ALKYLS WITH PENDANT OLEFINS ON CLAYS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2017-03-09 WO claimed
WO-2015065784-A1 NOVEL ALUMINUM ALKYL WITH C5 CYCLIC AND PENDENT OLEFIN POLYMERIZATION CATALYST EXXONMOBIL CHEMICAL PATENTS INC. (US) 2015-05-07 WO claimed
US-20150119540-A1 Novel Aluminum Alkyl With C5 Cyclic and Pendent Olefin Polymerization Catalyst EXXONMOBIL CHEMICAL PATENTS INC. 2015-04-30 US claimed
US-8088867-B2 Multiple catalyst system for olefin polymerization and polymers produced therefrom EXXONMOBIL CHEMICAL PATENTS INC. (US) 2012-01-03 US claimed
EP-1799726-B1 TRIALKYLALUMINUM TREATED SUPPORTS EXXONMOBIL CHEM PATENTS INC (US) 2011-07-13 EP claimed
US-7741417-B2 Preparation of polymerization catalyst activators utilizing indole-modified silica supports EXXONMOBIL CHEMICAL PATENTS INC. (US) 2010-06-22 US claimed
US-7385015-B2 Trialkylaluminum treated supports EXXONMOBIL CHEMICAL PATENTS INC. (US) 2008-06-10 US claimed
US-20070055028-A1 Preparation of polymerization catalyst activators utilizing indole-modified silica supports EXXONMOBIL CHEMICAL PATENTS INC. 2007-03-08 US claimed
US-20060079394-A1 Trialkylaluminum treated supports EXXONMOBIL CHEMICAL PATENTS INC. 2006-04-13 US claimed
US-20050148743-A1 polymerization catalyst systems comprising an ion-exchange layered silicate, an organoaluminum compound, and a heterocyclic compound EXXONMOBIL CHEMICAL PATENTS INC. 2005-07-07 US claimed
US-12275812-B2 Olefin resin, crosslinked product thereof, and production methods thereof MITSUI CHEMICALS, INC. (JP) 2025-04-15 US disclosed
US-20250026927-A1 Propylene-Based Blend Compositions EXXONMOBIL TECHNOLOGY & ENGINEERING COMPANY (US) 2025-01-23 US disclosed
US-11708434-B2 Silica quenching agents for use in polymerization process EXXONMOBIL CHEMICAL PATENTS INC. (US) 2023-07-25 US disclosed
US-5990242-A Propylene/ethylene-α-olefin block copolymer and process for processing the same SUMITOMO CHEMICAL CO., LTD. (JP) 1999-11-23 US disclosed
US-5912373-A Process for converting the achiral meso form of an ansa-metallocene complex into the chiral racemic form BASF AKTIENGESELLSCHAFT (DE) 1999-06-15 US disclosed
US-5892081-A REACTING TIN METALLOCENE WITH TRANSITION METAL HALIDE OR ALKOXIDE BASF AKTIENGESELLSCHAFT (DE) 1999-04-06 US disclosed
US-5840950-A Process for converting the achiral meso form or the racemate of an ansa-metallocene complex or mixtures thereof into one of its enantiomers BASF AKTIENGESELLSCHAFT (DE) 1998-11-24 US disclosed