SCHEMBL5189692

SCHEMBL5189692

CCCCCCCCCCCCc1cc(Cl)ccc1Cl

nearest known ligand 0.44

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TYR P14679 2/20 0.44
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
TP53 P04637 1/20 0.44
CYP3A4 P08684 1/20 0.44
ALOX5 P09917 1/20 0.44
MAPT P10636 1/20 0.44
ALOX15 P16050 1/20 0.44
TSHR P16473 1/20 0.44
HTT P42858 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
KCNH2 Q12809 4/20 0.44
CNR2 P34972 2/20 0.42
LIPG Q9Y5X9 1/20 0.42
CNR1 P21554 1/20 0.42
ABL1 P00519 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1310459 1.00 TYR (0.44) TYRMEN1KMT2ATP53CYP3A4
SCHEMBL5900913 1.00 TYR (0.44) TYRMEN1KMT2ATP53CYP3A4
SCHEMBL27951034 1.00 TYR (0.44) TYRMEN1KMT2ATP53CYP3A4
SCHEMBL6685016 0.98 TP53 (0.42) TYRMEN1KMT2ATP53CYP3A4
SCHEMBL30645684 0.92 MEN1 (0.44) TYRMEN1KMT2ATP53CYP3A4
SCHEMBL8641170 0.92 MEN1 (0.44) TYRMEN1KMT2ATP53CYP3A4
SCHEMBL11775528 0.85 ACLY (0.49) TYRMEN1KMT2ATP53CYP3A4
SCHEMBL16224885 0.85 ACLY (0.49) TYRMEN1KMT2ATP53CYP3A4
SCHEMBL21982535 0.85 TYR (0.49) TYRMEN1KMT2ATP53CYP3A4
SCHEMBL7224195 0.84 FLT1 (0.46) MEN1KMT2ATP53CYP3A4MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1853646-A1 INFERRED WATER ANALYSIS IN POLYPHENYLENE SULFIDE PRODUCTION CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2007-11-14 EP disclosed
WO-2006091935-A1 INFERRED WATER ANALYSIS IN POLYPHENYLENE SULFIDE PRODUCTION CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2006-08-31 WO disclosed
US-5256742-A Preparation of poly(arylene sulfide)s from poly(arylene sulfide disulfide) PHILLIPS PETROLEUM COMPANY (US) 1993-10-26 US disclosed
EP-0044184-A2 Blend of polyarylene sulfide and wholly aromatic polyester CELANESE CORPORATION (US) 1982-01-20 EP disclosed
US-4276397-A IMPROVED PROCESSABILITY TO FORM MOLDED ARTICLES CELANESE CORPORATION (US) 1981-06-30 US disclosed