SCHEMBL6685016

SCHEMBL6685016

CCCCCc1cc(Cl)ccc1Cl

nearest known ligand 0.44

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TP53 P04637 2/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
CYP3A4 P08684 1/20 0.42
ALOX5 P09917 1/20 0.42
MAPT P10636 1/20 0.42
TYR P14679 1/20 0.42
ALOX15 P16050 1/20 0.42
TSHR P16473 1/20 0.42
HTT P42858 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
CNR2 P34972 2/20 0.41
KCNH2 Q12809 4/20 0.41
CNR1 P21554 1/20 0.40
LIPG Q9Y5X9 1/20 0.39
SIGMAR1 Q99720 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
RAB9A P51151 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5900913 0.98 TYR (0.44) TP53MEN1KMT2ACYP3A4ALOX5
SCHEMBL5189692 0.98 TYR (0.44) TP53MEN1KMT2ACYP3A4ALOX5
SCHEMBL27951034 0.98 TYR (0.44) TP53MEN1KMT2ACYP3A4ALOX5
SCHEMBL1310459 0.98 TYR (0.44) TP53MEN1KMT2ACYP3A4ALOX5
SCHEMBL30645684 0.94 MEN1 (0.44) TP53MEN1KMT2ACYP3A4MAPT
SCHEMBL8641170 0.94 MEN1 (0.44) TP53MEN1KMT2ACYP3A4MAPT
SCHEMBL7224195 0.85 FLT1 (0.46) TP53MEN1KMT2ACYP3A4MAPT
SCHEMBL28316114 0.84 IDO1 (0.50) TP53MEN1KMT2ACYP3A4ALOX5
Ammonia Solution, Strong SCHEMBL14718591 0.83 FLT1 (0.45) TP53MEN1KMT2ACYP3A4MAPT
SCHEMBL11775528 0.82 ACLY (0.49) TP53MEN1KMT2ACYP3A4ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117820076-A Method for preparing 2, 6-dichlorotoluene by micro-channel reactor 盐城师范学院 2024-04-05 CN disclosed
EP-0985649-B1 Method for producing an aromatic compound having an alkyl group with at least three carbon atoms TORAY INDUSTRIES (JP) 2004-11-24 EP disclosed
US-6462248-B1 THROUGH CONVERSION, ISOMERIZATION AND/OR ADSORPTIVE SEPARATION OF AROMATIC COMPOUNDS TORAY INDUSTRIES, INC. (JP) 2002-10-08 US disclosed
EP-1007501-A1 PROCESS FOR PRODUCING DIPHENYLETHERS AND ESTERS THE DOW CHEMICAL COMPANY (US) 2000-06-14 EP disclosed
EP-0985649-A2 Method for producing an aromatic compound having an alkyl group with at least three carbon atoms TORAY INDUSTRIES, INC. (JP) 2000-03-15 EP disclosed
WO-1999010310-A1 PROCESS FOR PRODUCING DIPHENYLETHERS AND ESTERS THE DOW CHEMICAL COMPANY (US) 1999-03-04 WO disclosed