Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 4/20 | 0.34 |
| ▸ | CA2 | P00918 | 4/20 | 0.34 |
| ▸ | CA4 | P22748 | 4/20 | 0.34 |
| ▸ | CA9 | Q16790 | 4/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4332678 | 0.83 | TSHR (0.39) | PARP1TSHRCHRNB2CHRNA4CHRNB4 | |
| SCHEMBL5195457 | 0.82 | FHIT (0.34) | PARP1CA1CA2CA4CA9 | |
| Hydrochloric Acid SCHEMBL17560393 | 0.81 | TSHR (0.38) | PARP1TSHRCHRNB2CHRNA4CHRNB4 | |
| SCHEMBL5193793 | 0.81 | GBA2 (0.39) | PARP1CA1CA2CA4CA9 | |
| SCHEMBL5195326 | 0.77 | LMNA (0.39) | CHRNB2CHRNA4CHRNB4CHRNA3CA1 | |
| SCHEMBL2919209 | 0.76 | TSHR (0.36) | TSHRCA1CA2CA4CA9 | |
| SCHEMBL1149942 | 0.74 | PARP1 (0.50) | PARP1 | |
| SCHEMBL9098808 | 0.74 | PARP1 (0.50) | PARP1 | |
| SCHEMBL18706103 | 0.74 | LMNA (0.39) | CHRNA7KCNH2 | |
| SCHEMBL4340453 | 0.74 | TSHR (0.52) | TSHRCHRNB2CHRNA4CHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0968206-B8 | N-HETEROCYCLIC DERIVATIVES AS NOS INHIBITORS | BERLEX INC (US) | 2007-01-24 | — | — | EP | disclosed |
| EP-0968206-A1 | N-HETEROCYCLIC DERIVATIVES AS NOS INHIBITORS | BERLEX LABORATORIES, INC. (US) | 2000-01-05 | — | — | EP | disclosed |
| WO-1998037079-A1 | N-HETEROCYCLIC DERIVATIVES AS NOS INHIBITORS | BERLEX LABORATORIES, INC. (US) | 1998-08-27 | — | — | WO | disclosed |