SCHEMBL519034

SCHEMBL519034

OC[C@H]1OC(OCc2ccccc2)[C@@H](O)[C@@H](O)[C@@H]1O

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 2/20 0.57
SYNJ2 O15056 2/20 0.56
KDM4E B2RXH2 1/20 0.56
ABL1 P00519 1/20 0.56
ALPL P05186 1/20 0.56
POLB P06746 1/20 0.56
ALPI P09923 1/20 0.56
GAA P10253 1/20 0.56
MAPT P10636 1/20 0.56
ALPG P10696 1/20 0.56
PABPC1 P11940 1/20 0.56
RECQL P46063 1/20 0.56
GALK1 P51570 1/20 0.56
CASP7 P55210 1/20 0.56
CASP6 P55212 1/20 0.56
MCL1 Q07820 1/20 0.56
RIN1 Q13671 1/20 0.56
EIF4H Q15056 1/20 0.56
SLC5A2 P31639 1/20 0.54
TYR P14679 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8838916 1.00 SLC6A2 (0.57) SLC6A2SYNJ2KDM4EABL1ALPL
SCHEMBL18733414 1.00 SLC6A2 (0.57) SLC6A2SYNJ2KDM4EABL1ALPL
SCHEMBL19479665 1.00 SLC6A2 (0.57) SLC6A2SYNJ2KDM4EABL1ALPL
SCHEMBL7152381 1.00 SLC6A2 (0.57) SLC6A2SYNJ2KDM4EABL1ALPL
SCHEMBL5265603 1.00 SLC6A2 (0.57) SLC6A2SYNJ2KDM4EABL1ALPL
SCHEMBL8838912 1.00 SLC6A2 (0.57) SLC6A2SYNJ2KDM4EABL1ALPL
SCHEMBL5026363 1.00 SLC6A2 (0.57) SLC6A2SYNJ2KDM4EABL1ALPL
SCHEMBL2621553 1.00 SLC6A2 (0.57) SLC6A2SYNJ2KDM4EABL1ALPL
SCHEMBL5026358 1.00 SLC6A2 (0.57) SLC6A2SYNJ2KDM4EABL1ALPL
SCHEMBL9849310 1.00 SLC6A2 (0.57) SLC6A2SYNJ2KDM4EABL1ALPL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12023357-B2 Rejuvenated aged hematopoietic stem cells and methods of use HACKENSACK UNIVERSITY MEDICAL CENTER (US) 2024-07-02 US disclosed
US-20220072098-A1 BOLAAMPHIPHILIC COMPOUNDS, COMPOSITIONS AND USES THEREOF LAUREN SCIENCES LLC 2022-03-10 US disclosed
EP-3808177-A1 NOVEL LIPIDS AND COMPOSITIONS FOR THE DELIVERY OF THERAPEUTICS Arbutus Biopharma Corporation (CA) 2021-04-21 EP disclosed
US-10835612-B2 Lipids and compositions for the delivery of therapeutics ARBUTUS BIOPHARMA CORPORATION (CA) 2020-11-17 US disclosed
EP-3238738-B1 NOVEL LIPIDS AND COMPOSITIONS FOR THE DELIVERY OF THERAPEUTICS ARBUTUS BIOPHARMA CORP (CA) 2020-09-23 EP disclosed
US-20190231823-A1 REJUVENATED AGED HEMATOPOIETIC STEM CELLS AND METHODS OF USE HACKENSACK UNIVERSITY MEDICAL CENTER 2019-08-01 US disclosed
US-20190216895-A1 BOLAAMPHIPHILIC COMPOUNDS, COMPOSITIONS AND USES THEREOF LAUREN SCIENCES LLC (US) 2019-07-18 US disclosed
US-20180125985-A1 NOVEL LIPIDS AND COMPOSITIONS FOR THE DELIVERY OF THERAPEUTICS ARBUTUS BIOPHARMA CORPORATION (CA) 2018-05-10 US disclosed
US-20180064807-A1 NOVEL LIPIDS AND COMPOSITIONS FOR THE DELIVERY OF THERAPEUTICS ARBUTUS BIOPHARMA CORPORATION (CA) 2018-03-08 US disclosed
EP-3283060-A1 BOLAAMPHIPHILIC COMPOUNDS, COMPOSITIONS AND USES THEREOF Lauren Sciences LLC (US) 2018-02-21 EP disclosed
US-6462193-B1 ADDING 3-AZIDO-2-HYDROXYPROPANALDEHYDE WITH DIHYDROXYACETONE PHOSPHATE USING AN ALDOLASE, HYDROLYZING THE INTERMEDIATE WITH ACID PHOSPHATASE, ISOMERIZING USING AN ISOMERASE, CYCLIZING USING REDUCTIVE AMINATION TO PRODUCE TETRAHYDROXYAZEPINE THE SCRIPPS RESEARCH INSTITUTE 2002-10-08 US disclosed
US-20010028977-A1 Charging, discharging efficiency; vanadium electrolyte JD HOLDING INC. (KY) 2001-10-11 US disclosed
US-6294521-B1 SUGAR PHOSPHATES AUSTRALIAN NATIONAL UNIVERSITY (AU) 2001-09-25 US disclosed
US-6143443-A ALL-VANADIUM REDOX BATTERY, COMPRISING THE STABILIZED ELECTROLYTE PINNACLE ARB LIMITED (AU) 2000-11-07 US disclosed
WO-1998037218-A1 HYDROXYAZEPANES AS INHIBITORS OF GLYCOSIDASE AND HIV PROTEASE THE SCRIPPS RESEARCH INSTITUTE (US) 1998-08-27 WO disclosed
EP-0829104-A1 HIGH ENERGY DENSITY VANADIUM ELECTROLYTE SOLUTIONS, METHODS OF PREPARATION THEREOF AND ALL-VANADIUM REDOX CELLS AND BATTERIES CONTAINING HIGH ENERGY VANADIUM ELECTROLYTE SOLUTIONS UNISEARCH LIMITED (AU) 1998-03-18 EP disclosed
EP-0729648-A4 STABILISED ELECTROLYTE SOLUTIONS, METHODS OF PREPARATION THEREOF AND REDOX CELLS AND BATTERIES CONTAINING STABILISED ELECTROLYTE SOLUTIONS UNISEARCH LTD (AU) 1997-01-02 EP disclosed
WO-1996035239-A1 HIGH ENERGY DENSITY VANADIUM ELECTROLYTE SOLUTIONS, METHODS OF PREPARATION THEREOF AND ALL-VANADIUM REDOX CELLS AND BATTERIES CONTAINING HIGH ENERGY VANADIUM ELECTROLYTE SOLUTIONS UNISEARCH LIMITED (AU) 1996-11-07 WO disclosed
EP-0729648-A1 STABILISED ELECTROLYTE SOLUTIONS, METHODS OF PREPARATION THEREOF AND REDOX CELLS AND BATTERIES CONTAINING STABILISED ELECTROLYTE SOLUTIONS UNISEARCH LIMITED (AU) 1996-09-04 EP disclosed
WO-1995012219-A1 STABILISED ELECTROLYTE SOLUTIONS, METHODS OF PREPARATION THEREOF AND REDOX CELLS AND BATTERIES CONTAINING STABILISED ELECTROLYTE SOLUTIONS UNISEARCH LIMITED (AU) 1995-05-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180125985-A1 NOVEL LIPIDS AND COMPOSITIONS FOR THE DELIVERY OF THERAPEUTICS CETP, LCAT, NPC1L1 SLC6A2 2280/4885SYNJ2 602/4885KDM4E 3941/4885
US-20190216895-A1 BOLAAMPHIPHILIC COMPOUNDS, COMPOSITIONS AND USES THEREOF GFRA2, GFRA1, NGF SLC6A2 239/4885SYNJ2 3466/4885KDM4E 4648/4885
US-20220072098-A1 BOLAAMPHIPHILIC COMPOUNDS, COMPOSITIONS AND USES THEREOF GFRA2, GFRA1, NGF SLC6A2 269/4885SYNJ2 3438/4885KDM4E 4638/4885
US-20180064807-A1 NOVEL LIPIDS AND COMPOSITIONS FOR THE DELIVERY OF THERAPEUTICS CETP, LCAT, NPC1L1 SLC6A2 2307/4885SYNJ2 609/4885KDM4E 3900/4885
US-10835612-B2 Lipids and compositions for the delivery of therapeutics CETP, LCAT, LIPA SLC6A2 1701/4885SYNJ2 710/4885KDM4E 3778/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.