Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 3/20 | 0.47 |
| ▸ | ACACB | O00763 | 13/20 | 0.45 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.41 |
| ▸ | IGF1R | P08069 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5192204 | 0.90 | NOS2 (0.44) | NOS2POLB | |
| SCHEMBL5194534 | 0.90 | ACACB (0.52) | ACACB | |
| SCHEMBL5192349 | 0.88 | NOS2 (0.46) | NOS2ACACB | |
| SCHEMBL5193161 | 0.88 | NOS2 (0.49) | NOS2 | |
| SCHEMBL5191688 | 0.87 | NOS2 (0.51) | NOS2ACACBALKIGF1R | |
| SCHEMBL5190408 | 0.83 | NOS2 (0.61) | NOS2ALK | |
| SCHEMBL5190457 | 0.82 | NOS2 (0.54) | NOS2ACACB | |
| SCHEMBL5190216 | 0.81 | NOS2 (0.45) | NOS2ACACBPOLB | |
| SCHEMBL5190602 | 0.79 | NOS2 (0.61) | NOS2 | |
| SCHEMBL5192064 | 0.79 | NOS2 (0.51) | NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1754703-A2 | N-Heterocyclic derivatives as nos inhibitors | Berlex, Inc. (US) | 2007-02-21 | — | — | EP | claimed |
| EP-1754703-A2 | N-Heterocyclic derivatives as nos inhibitors | Berlex, Inc. (US) | 2007-02-21 | — | — | EP | disclosed |
| EP-0968206-B1 | N-HETEROCYCLIC DERIVATIVES AS NOS INHIBITORS | BERLEX LAB (US) | 2006-11-15 | — | — | EP | disclosed |