Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.50 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.48 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4473275 | 0.83 | ALDH1A1 (0.60) | KMT2AALDH1A1TDP1L3MBTL1KDM4E | |
| Hydrochloric Acid SCHEMBL21640577 | 0.82 | ALDH1A1 (0.58) | KMT2AALDH1A1TDP1L3MBTL1KDM4E | |
| SCHEMBL5123195 | 0.80 | TDP1 (0.69) | KMT2AALDH1A1TDP1L3MBTL1KDM4E | |
| SCHEMBL2994259 | 0.78 | ALDH1A1 (0.57) | KMT2AALDH1A1TDP1L3MBTL1KDM4E | |
| SCHEMBL9906308 | 0.78 | ALDH1A1 (0.57) | KMT2AALDH1A1TDP1L3MBTL1KDM4E | |
| SCHEMBL5191646 | 0.78 | ALDH1A1 (0.59) | KMT2AALDH1A1MEN1HPGDHSD17B10 | |
| SCHEMBL5119694 | 0.77 | TDP1 (0.66) | KMT2AALDH1A1TDP1L3MBTL1KDM4E | |
| SCHEMBL5124500 | 0.77 | TDP1 (0.66) | KMT2AALDH1A1TDP1L3MBTL1KDM4E | |
| SCHEMBL18977797 | 0.77 | TDP1 (0.62) | KMT2AALDH1A1TDP1L3MBTL1KDM4E | |
| SCHEMBL5418744 | 0.76 | TDP1 (0.64) | KMT2AALDH1A1TDP1L3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1363925-B8 | MACROLIDE ANTIBIOTICS | GLAXO GROUP LTD (GB) | 2007-04-25 | — | — | EP | disclosed |
| EP-1363925-A1 | MACROLIDE ANTIBIOTICS | GLAXO GROUP LIMITED (GB) | 2003-11-26 | — | — | EP | disclosed |
| WO-2002050091-A1 | MACROLIDE ANTIBIOTICS | GLAXO GROUP LIMITED (GB) | 2002-06-27 | — | — | WO | disclosed |