SCHEMBL5193264

SCHEMBL5193264

CCCC(=O)CCC(C)[C]=O

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 5/20 0.37
HDAC2 Q92769 5/20 0.37
HDAC3 O15379 4/20 0.37
HDAC8 Q9BY41 4/20 0.37
FFAR3 O14843 3/20 0.37
CES2 O00748 1/20 0.35
CES1 P23141 1/20 0.35
TSHR P16473 1/20 0.32
ALDH1A1 P00352 1/20 0.31
IAPP P10997 2/20 0.31
FFAR4 Q5NUL3 1/20 0.31
FFAR1 O14842 1/20 0.31
MAPT P10636 1/20 0.30
KMT2A Q03164 1/20 0.30
CHRM1 P11229 1/20 0.30
AKR1A1 P14550 1/20 0.30
CHRM3 P20309 1/20 0.30
HTR2A P28223 1/20 0.30
HTR2C P28335 1/20 0.30
ADRA1A P35348 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3160334 0.80 HDAC3 (0.39) HDAC1HDAC2HDAC3HDAC8FFAR3
SCHEMBL8011214 0.77
SCHEMBL109486 0.77 CA1 (0.50) HDAC1HDAC2HDAC3HDAC8FFAR3
SCHEMBL7064870 0.75
SCHEMBL2404264 0.75 ALDH1A1 (0.46) HDAC1HDAC2HDAC3HDAC8FFAR3
SCHEMBL271616 0.73
SCHEMBL26101257 0.73 TSHR (0.44) HDAC1HDAC2HDAC3HDAC8FFAR3
SCHEMBL11069921 0.73 TSHR (0.40) HDAC1HDAC2HDAC3HDAC8FFAR3
SCHEMBL22339977 0.73 ALDH1A1 (0.45) HDAC1HDAC2HDAC3HDAC8FFAR3
SCHEMBL6769545 0.73 GABRP (0.56) HDAC1HDAC2HDAC3HDAC8FFAR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1424058-B1 Make-up process for eyelashes with a composition comprising a tacky wax. OREAL (FR) 2007-07-18 EP claimed