Ethylenediamine

Ethylenediamine

SCHEMBL5193597

NCCN.O=P(O)(O)C(N(CCN(C(P(=O)(O)O)P(=O)(O)O)C(P(=O)(O)O)P(=O)(O)O)C(P(=O)(O)O)P(=O)(O)O)P(=O)(O)O

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D

The experimentally established mechanism targets of Ethylenediamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
FDPS P14324 3/20 0.43
ALDH1A1 P00352 1/20 0.42
ANPEP P15144 2/20 0.39
LMNA P02545 1/20 0.39
CYP3A4 P08684 1/20 0.39
NFKB1 P19838 1/20 0.39
BLM P54132 1/20 0.39
PMP22 Q01453 1/20 0.39
ERAP2 Q6P179 1/20 0.39
GABBR2 O75899 2/20 0.36
GABBR1 Q9UBS5 2/20 0.36
OTC P00480 1/20 0.33
LAP3 P28838 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylenediamine SCHEMBL14694305 1.00 FDPS (0.43) FDPSALDH1A1ANPEPLMNACYP3A4
SCHEMBL242910 0.90 FDPS (0.43) FDPSALDH1A1ANPEPLMNACYP3A4
SCHEMBL38156 0.89 FDPS (0.50) FDPSALDH1A1ANPEPLMNABLM
Ammonia Solution, Strong SCHEMBL3279112 0.87 FDPS (0.48) FDPSANPEPERAP2LAP3
Water SCHEMBL7073557 0.87 FDPS (0.48) FDPSANPEPERAP2LAP3
Ethylenediamine SCHEMBL1557836 0.87 FDPS (0.57) FDPSALDH1A1GABBR2GABBR1LAP3
Medronic Acid SCHEMBL11402591 0.86 FDPS (0.47) FDPSALDH1A1ANPEPLMNACYP3A4
SCHEMBL12231067 0.82 FDPS (0.44) FDPS
SCHEMBL2421676 0.82 ANPEP (0.39) FDPSALDH1A1ANPEPLMNACYP3A4
Ethylenediamine SCHEMBL1558198 0.81 FDPS (0.54) FDPSALDH1A1ANPEPLMNACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1141212-B1 PASTY WASHING AGENT ECOLAB INC (US) 2007-08-08 EP disclosed
EP-1133547-B2 ENCAPSULATED DETERGENT HENKEL KGAA (DE) 2006-10-04 EP disclosed
WO-2006048047-A1 BIOCIDIC DETERGENT ECOLAB INC. (US) 2006-05-11 WO disclosed
EP-1226226-B1 PASTE-LIKE DETERGENT ECOLAB INC (US) 2006-02-08 EP disclosed
EP-0879874-B1 Encapsulated detergent HENKEL KGAA (DE) 2003-12-10 EP disclosed
EP-0954559-B1 PASTELIKE DETERGENT AND CLEANING AGENT ECOLAB GMBH & CO OHG (DE) 2002-10-23 EP disclosed
EP-1133547-B1 ENCAPSULATED DETERGENT HENKEL KGAA (DE) 2002-09-18 EP disclosed
WO-2002012431-A1 PASTY PERACIDS ECOLAB GMBH & CO. OHG (DE) 2002-02-14 WO disclosed
EP-0929630-B1 PASTE-LIKE WASHING AND CLEANING AGENT HENKEL ECOLAB GMBH & CO OHG (DE) 2001-12-12 EP disclosed
EP-1141212-A1 PASTY WASHING AGENT HENKEL-ECOLAB GmbH & CO. OHG (DE) 2001-10-10 EP disclosed
EP-0721498-A1 PASTY WASHING AGENT Henkel Kommanditgesellschaft auf Aktien (DE) 1996-07-17 EP disclosed
WO-1995009229-A1 PASTY WASHING AGENT HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1995-04-06 WO disclosed
EP-0094119-B1 STABLE LIQUID DETERGENT COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1986-11-12 EP disclosed
EP-0060710-B1 LIQUID DETERGENT COMPOSITIONS CONTAINING ALPHA-AMINE OXIDE SURFACTANTS THE PROCTER & GAMBLE COMPANY (US) 1985-08-28 EP disclosed
US-4537706-A ANIONIC SURFACTANT, FATTY ACID THE PROCTER & GAMBLE COMPANY (US) 1985-08-27 US disclosed
US-4537707-A Liquid detergents containing boric acid and formate to stabilize enzymes THE PROCTER & GAMBLE COMPANY (US) 1985-08-27 US disclosed
US-4438024-A ALKYL AMINE OXIDE, POLYETHOXYLATE SULFATE, ETHANOLAMINE, NITRILOTRIACETATE AND ARYLSULFONATES THE PROCTER & GAMBLE COMPANY (US) 1984-03-20 US disclosed
US-4436653-A NONIONIC SURFACTANTS, AMINE OXIDES THE PROCTER & GAMBLE COMPANY (US) 1984-03-13 US disclosed
US-4405483-A GELATION OF AN ACIDIC AQUEOUS DIPERSION OF A ZEOLITE; MIXING WITH OTHER INGREDIANTS TO PROVIDE A BASIC SOLUTION THE PROCTER & GAMBLE COMPANY (US) 1983-09-20 US disclosed
US-4397776-A COLD WATER DETERGENTS THE PROCTER & GAMBLE COMPANY (US) 1983-08-09 US disclosed