Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | DHODH | Q02127 | 3/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.42 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | GABRP | O00591 | 1/20 | 0.41 |
| ▸ | GABRD | O14764 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3498365 | 0.73 | MEN1 (0.77) | SMN1; SMN2ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL14252651 | 0.72 | ALDH1A1 (0.54) | SMN1; SMN2ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL16577109 | 0.71 | MEN1 (0.55) | SMN1; SMN2ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL17647519 | 0.71 | SMN1; SMN2 (0.55) | SMN1; SMN2ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL23574762 | 0.71 | RXRB (0.49) | SMN1; SMN2ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL70795 | 0.70 | SMN1; SMN2 (0.65) | SMN1; SMN2ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL9784598 | 0.70 | ALDH1A1 (0.51) | SMN1; SMN2ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL5193709 | 0.70 | SMN1; SMN2 (0.54) | SMN1; SMN2ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL23574229 | 0.70 | AKR1C2 (0.48) | SMN1; SMN2ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL4677848 | 0.70 | ALDH1A1 (0.57) | SMN1; SMN2ALDH1A1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070232594-A1 | Aromatic amide derivatives, medicinal compositions containing the same, medical uses of both | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2007-10-04 | — | — | US | disclosed |
| EP-1813603-A1 | AROMATIC AMIDE DERIVATIVES, MEDICINAL COMPOSITIONS CONTAINING THE SAME, MEDICAL USES OF BOTH | Kissei Pharmaceutical Co., Ltd. (JP) | 2007-08-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070232594-A1 | Aromatic amide derivatives, medicinal compositions containing the same, medical uses of both | AVPR2, AVPR1A, AVPR1B | SMN1; SMN2 2669/4885ALDH1A1 1557/4885MEN1 1330/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.