SCHEMBL5193740

SCHEMBL5193740

CCCCCCC[C@H]1O[C@@H]1C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.49
FASN P49327 1/20 0.49
MAPT P10636 1/20 0.42
ALOX5 P09917 1/20 0.42
PPARG P37231 5/20 0.40
PPARD Q03181 5/20 0.40
PPARA Q07869 5/20 0.40
HDAC11 Q96DB2 4/20 0.40
TSHR P16473 3/20 0.40
GPR84 Q9NQS5 3/20 0.40
ALDH1A1 P00352 2/20 0.40
TLR2 O60603 2/20 0.40
TDP1 Q9NUW8 2/20 0.40
FABP4 P15090 2/20 0.40
PTPN1 P18031 2/20 0.40
SLC22A6 Q4U2R8 1/20 0.40
SLC22A8 Q8TCC7 1/20 0.40
MEN1 O00255 1/20 0.40
ESR1 P03372 1/20 0.40
ALOX15 P16050 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL232466 1.00 POLB (0.49) POLBFASNMAPTALOX5PPARG
SCHEMBL7345807 1.00 POLB (0.49) POLBFASNMAPTALOX5PPARG
SCHEMBL7343023 1.00 POLB (0.49) POLBFASNMAPTALOX5PPARG
SCHEMBL7345814 1.00 POLB (0.49) POLBFASNMAPTALOX5PPARG
SCHEMBL7351206 1.00 POLB (0.49) POLBFASNMAPTALOX5PPARG
SCHEMBL5197496 1.00 POLB (0.49) POLBFASNMAPTALOX5PPARG
SCHEMBL290361 1.00 POLB (0.49) POLBFASNMAPTALOX5PPARG
SCHEMBL7753268 1.00 POLB (0.49) POLBFASNMAPTALOX5PPARG
SCHEMBL7344570 1.00 POLB (0.49) POLBFASNMAPTALOX5PPARG
SCHEMBL7347077 1.00 POLB (0.49) POLBFASNMAPTALOX5PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210324009-A1 ANTI-BACTERIAL CALCIUM-DEPENDENT ANTIBIOTIC (CDA) ANALOGS AND METHODS OF TREATING BACTERIAL INFECTIONS THE UNIVERSITY OF HONG KONG (CN) 2021-10-21 US disclosed
EP-1403260-B1 Optically active epoxy compounds and processes for their production TOSOH CORP (JP) 2007-08-08 EP disclosed
US-7169944-B2 Optically active epoxy compounds and processes for their production TOSOH CORPORATION (JP) 2007-01-30 US disclosed
US-20040063979-A1 Optically active epoxy compounds and processes for their production TOSOH CORPORATION (JP) 2004-04-01 US disclosed
EP-1403260-A2 Optically active epoxy compounds and processes for their production Tosoh Corporation (JP) 2004-03-31 EP disclosed
EP-0761642-B1 Process for preparing 2-amino-1, 3-alkanediol or a derivative thereof, process for preparing optically active dihydrosphingosine derivatives and intermediates used in that process TAKASAGO PERFUMERY CO LTD (JP) 2001-02-07 EP disclosed
US-5925792-A Process for preparing 2-amino-1,3-alkanediol or derivative thereof, process for preparing optically active dihydrosphingosine derivative, and intermediates for optically active dihydrosphingosine derivative TAKASAGO INTERNATIONAL CORPORATION (JP) 1999-07-20 US disclosed
EP-0761642-A2 Process for preparing 2-amino-1, 3-alkanediol or a derivative thereof, process for preparing optically active dihydrosphingosine derivatives and intermediates used in that process Takasago International Corporation (JP) 1997-03-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210324009-A1 ANTI-BACTERIAL CALCIUM-DEPENDENT ANTIBIOTIC (CDA) ANALOGS AND METHODS OF TREATING BACTERIAL INFECTIONS ORAI1, CASR, CALCA POLB 3300/4885FASN 2342/4885MAPT 2933/4885
US-20040063979-A1 Optically active epoxy compounds and processes for their production CYP51A1, CYP11B1, PTGES POLB 1436/4885FASN 164/4885MAPT 4136/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.