⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1439785 | 1.00 | — | — | |
| SCHEMBL17958893 | 1.00 | — | — | |
| SCHEMBL519196 | 0.93 | — | — | |
| SCHEMBL518656 | 0.91 | ALDH1A1 (0.35) | — | |
| SCHEMBL28294442 | 0.84 | — | — | |
| SCHEMBL82575 | 0.84 | — | — | |
| SCHEMBL1461766 | 0.84 | — | — | |
| SCHEMBL519608 | 0.84 | SMN1; SMN2 (0.35) | — | |
| SCHEMBL518568 | 0.80 | GABRA5 (0.32) | — | |
| SCHEMBL519260 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 260 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE49481-E1 | Compounds for the treatment and prophylaxis of respiratory syncytial virus disease | HOFFMANN-LA ROCHE INC. (US) | 2023-04-04 | — | — | US | claimed |
| CN-107873028-A | Polycyclic amide derivatives useful as CDK9 inhibitors | 阿斯利康(瑞典)有限公司 | 2018-04-03 | — | — | CN | claimed |
| EP-3078669-A1 | SUBSTITUTED (2R, 3R, 5R)-3-HYDROXY-(5-PYRIMIDIN-1-YL) TETRAHYDROFURAN-2-YLMETHYL ARYL PHOSPHORAMIDATES | IVASHCHENKO, Andrey Alexandrovich (RU) | 2016-10-12 | — | — | EP | claimed |
| EP-3055316-A1 | SUBSTITUTED (S)-(2R,3R,5R)-3-HYDROXY-(5-PYRIMIDIN-L-YL)TETRAHYDROFURAN-2- YLMETHYL ARYL PHOSPHORAMIDATE | Alla Chem, LLC. (US) | 2016-08-17 | — | — | EP | claimed |
| EP-2742039-B1 | COMPOUNDS FOR THE TREATMENT AND PROPHYLAXIS OF RESPIRATORY SYNCYTIAL VIRUS DISEASE | HOFFMANN LA ROCHE (CH) | 2015-09-16 | — | — | EP | claimed |
| WO-2015054706-A1 | SUBSTITUTED (S)-(2R,3R,5R)-3-HYDROXY-(5-PYRIMIDIN-L-YL)TETRAHYDROFURAN-2- YLMETHYL ARYL PHOSPHORAMIDATE | ALLA CHEM, LLC (US) | 2015-04-16 | — | — | WO | claimed |
| US-8889701-B1 | Substituted (S)-(2R,3R,5R)-3-hydroxy-(5-pyrimidin-1-yl)tetrahydrofuran-2-ylmethyl aryl phosphoramidate | ALLA CHEM LLC (US) | 2014-11-18 | — | — | US | claimed |
| US-8871756-B2 | Compounds for the treatment and prophylaxis of Respiratory Syncytial Virus disease | HOFFMANN-LA ROCHE INC. (US) | 2014-10-28 | — | — | US | claimed |
| EP-2742039-A1 | COMPOUNDS FOR THE TREATMENT AND PROPHYLAXIS OF RESPIRATORY SYNCYTIAL VIRUS DISEASE | F. Hoffmann-La Roche AG (CH) | 2014-06-18 | — | — | EP | claimed |
| US-20130196974-A1 | COMPOUNDS FOR THE TREATMENT AND PROPHYLAXIS OF RESPIRATORY SYNCYTIAL VIRUS DISEASE | HOFFMANN-LA ROCHE INC. | 2013-08-01 | — | — | US | claimed |
| EP-1797051-A1 | BENZOXAZINE AND QUINOXALINE DERIVATIVES AND USES | F. Hoffmann-Roche AG (CH) | 2007-06-20 | — | — | EP | claimed |
| EP-1768973-A1 | SUBSTITUTED QUINOLONES | AiCuris GmbH & Co. KG (DE) | 2007-04-04 | — | — | EP | claimed |
| WO-2006037481-A1 | BENZOXAZINE AND QUINOXALINE DERIVATIVES AND USES | F.HOFFMANN-LA ROCHE AG (CH) | 2006-04-13 | — | — | WO | claimed |
| WO-2006008046-A1 | SUBSTITUTED QUINOLONES | AICURIS GMBH & CO. KG (DE) | 2006-01-26 | — | — | WO | claimed |
| CN-1265670-A | Dipeptides and related compounds that inhibit VLA-4 mediated leukocyte adhesion | ELAND PHARMACEUTICALS CO (US) | 2000-09-06 | — | — | CN | claimed |
| JP-H09501913-A | — | — | 1997-02-25 | — | — | JP | claimed |
| EP-0738154-A1 | N-TERMINUS MODIFIED ANALOGS OF LHRH | Abbott Laboratories (US) | 1996-10-23 | — | — | EP | claimed |
| EP-0738154-A4 | N-TERMINUS MODIFIED ANALOGS OF LHRH | ABBOTT LAB (US) | 1996-04-12 | — | — | EP | claimed |
| US-5502035-A | N-terminus modified analogs of LHRH | TAP HOLDINGS INC. (US) | 1996-03-26 | — | — | US | claimed |
| WO-1995004541-A1 | N-TERMINUS MODIFIED ANALOGS OF LHRH | ABBOTT LABORATORIES (US) | 1995-02-16 | — | — | WO | claimed |