Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 8/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 8/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 6/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.38 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31025938 | 0.71 | KEAP1 (0.48) | KEAP1NFE2L2KIF11CHRM2CHRM1 | |
| SCHEMBL21495109 | 0.69 | KEAP1 (0.47) | KEAP1NFE2L2KIF11CHRM2CHRM1 | |
| SCHEMBL27406395 | 0.69 | TSHR (0.44) | TSHRTDP1BLM | |
| SCHEMBL7438264 | 0.69 | TSHR (0.44) | TSHRTDP1BLM | |
| SCHEMBL9940816 | 0.68 | KEAP1 (0.55) | KEAP1NFE2L2CHRM2CHRM1CHRM3 | |
| SCHEMBL28062010 | 0.68 | KEAP1 (0.54) | KEAP1NFE2L2KIF11CHRM2CHRM1 | |
| SCHEMBL2788657 | 0.68 | KEAP1 (0.59) | KEAP1NFE2L2KIF11CHRM2CHRM1 | |
| SCHEMBL5370794 | 0.67 | HPGD (0.39) | KEAP1NFE2L2KIF11CHRM2CHRM1 | |
| SCHEMBL4081989 | 0.67 | KEAP1 (0.53) | KEAP1NFE2L2KIF11CHRM2CHRM1 | |
| SCHEMBL22257216 | 0.66 | KEAP1 (0.56) | KEAP1NFE2L2CHRM2CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1403260-B1 | Optically active epoxy compounds and processes for their production | TOSOH CORP (JP) | 2007-08-08 | — | — | EP | claimed |
| US-20040063979-A1 | Optically active epoxy compounds and processes for their production | TOSOH CORPORATION (JP) | 2004-04-01 | — | — | US | claimed |
| EP-1403260-A2 | Optically active epoxy compounds and processes for their production | Tosoh Corporation (JP) | 2004-03-31 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040063979-A1 | Optically active epoxy compounds and processes for their production | CYP51A1, CYP11B1, PTGES | KEAP1 345/4885NFE2L2 187/4885KIF11 3071/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.