Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.47 |
| ▸ | CMA1 | P23946 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | PRKAB2 | O43741 | 4/20 | 0.44 |
| ▸ | PRKAG1 | P54619 | 4/20 | 0.44 |
| ▸ | PRKAA2 | P54646 | 4/20 | 0.44 |
| ▸ | PRKAA1 | Q13131 | 4/20 | 0.44 |
| ▸ | PRKAG3 | Q9UGI9 | 4/20 | 0.44 |
| ▸ | PRKAG2 | Q9UGJ0 | 4/20 | 0.44 |
| ▸ | PRKAB1 | Q9Y478 | 4/20 | 0.44 |
| ▸ | RARA | P10276 | 1/20 | 0.42 |
| ▸ | RARB | P10826 | 1/20 | 0.42 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | ASPH | Q12797 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5461052 | 0.88 | THRA (0.47) | THRATHRBFFAR4GAAS1PR1 | |
| SCHEMBL16726472 | 0.86 | THRA (0.64) | THRATHRBRARARARBPTPN11 | |
| SCHEMBL14430363 | 0.85 | THRA (0.50) | THRATHRBPRKAB2PRKAG1PRKAA2 | |
| SCHEMBL26641029 | 0.83 | KDM4E (0.50) | THRATHRBALDH1A1 | |
| SCHEMBL20556512 | 0.82 | THRA (0.70) | THRATHRBRARBPTPN11 | |
| SCHEMBL5195144 | 0.82 | THRA (0.48) | THRATHRBFFAR4RARARARB | |
| SCHEMBL27195874 | 0.82 | THRA (0.63) | THRATHRBPDK2ALDH1A1 | |
| SCHEMBL5191638 | 0.82 | TDP1 (0.45) | THRATHRBFFAR4GAAALDH1A1 | |
| SCHEMBL14104475 | 0.82 | ALDH1A1 (0.53) | GAAPRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL1941122 | 0.80 | THRA (0.45) | THRATHRBALDH1A1ASPHSRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070232594-A1 | Aromatic amide derivatives, medicinal compositions containing the same, medical uses of both | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2007-10-04 | — | — | US | disclosed |
| US-20070232594-A1 | Aromatic amide derivatives, medicinal compositions containing the same, medical uses of both | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2007-10-04 | — | — | US | disclosed |
| US-20070232594-A1 | Aromatic amide derivatives, medicinal compositions containing the same, medical uses of both | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2007-10-04 | — | — | US | disclosed |
| EP-1813603-A1 | AROMATIC AMIDE DERIVATIVES, MEDICINAL COMPOSITIONS CONTAINING THE SAME, MEDICAL USES OF BOTH | Kissei Pharmaceutical Co., Ltd. (JP) | 2007-08-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070232594-A1 | Aromatic amide derivatives, medicinal compositions containing the same, medical uses of both | AVPR2, AVPR1A, AVPR1B | THRA 493/4885THRB 499/4885FFAR4 99/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.