Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 7/20 | 0.49 |
| ▸ | MAOB | P27338 | 4/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14430289 | 0.88 | L3MBTL1 (0.51) | ALDH1A1L3MBTL1MAOBTDP1TSHR | |
| SCHEMBL17958912 | 0.87 | MAOB (0.59) | ALDH1A1L3MBTL1MAOBTDP1TSHR | |
| SCHEMBL5195459 | 0.87 | MAOB (0.49) | ALDH1A1L3MBTL1MAOBTDP1TSHR | |
| SCHEMBL5063445 | 0.87 | ALDH1A1 (0.50) | ALDH1A1L3MBTL1MAOBTDP1TSHR | |
| SCHEMBL5194255 | 0.86 | MEN1 (0.53) | ALDH1A1L3MBTL1MAOBTDP1TSHR | |
| SCHEMBL5193405 | 0.86 | L3MBTL1 (0.50) | ALDH1A1L3MBTL1MAOBTDP1TSHR | |
| SCHEMBL25683662 | 0.85 | L3MBTL1 (0.55) | ALDH1A1L3MBTL1MAOBTDP1TSHR | |
| SCHEMBL5194512 | 0.84 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1MAOBTDP1TSHR | |
| SCHEMBL25683635 | 0.82 | DHODH (0.54) | ALDH1A1L3MBTL1TDP1TSHRCYP3A4 | |
| SCHEMBL5191841 | 0.82 | PDE3B (0.44) | ALDH1A1L3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070232594-A1 | Aromatic amide derivatives, medicinal compositions containing the same, medical uses of both | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2007-10-04 | — | — | US | disclosed |
| US-20070232594-A1 | Aromatic amide derivatives, medicinal compositions containing the same, medical uses of both | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2007-10-04 | — | — | US | disclosed |
| US-20070232594-A1 | Aromatic amide derivatives, medicinal compositions containing the same, medical uses of both | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2007-10-04 | — | — | US | disclosed |
| EP-1813603-A1 | AROMATIC AMIDE DERIVATIVES, MEDICINAL COMPOSITIONS CONTAINING THE SAME, MEDICAL USES OF BOTH | Kissei Pharmaceutical Co., Ltd. (JP) | 2007-08-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070232594-A1 | Aromatic amide derivatives, medicinal compositions containing the same, medical uses of both | AVPR2, AVPR1A, AVPR1B | ALDH1A1 1557/4885L3MBTL1 2769/4885MAOB 892/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.