Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 12/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 12/20 | 0.57 |
| ▸ | MAPT | P10636 | 12/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.57 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5190926 | 1.00 | MEN1 (0.57) | MEN1KMT2AMAPTALDH1A1ABCG2 | |
| SCHEMBL6733051 | 0.81 | MEN1 (0.64) | MEN1KMT2AMAPTALDH1A1ABCG2 | |
| SCHEMBL5190207 | 0.79 | MAPT (0.59) | MEN1KMT2AMAPTALDH1A1PKM | |
| SCHEMBL5190214 | 0.79 | MAPT (0.59) | MEN1KMT2AMAPTALDH1A1PKM | |
| SCHEMBL12443555 | 0.79 | AMY1A (0.49) | MEN1KMT2AMAPTALDH1A1ABCG2 | |
| SCHEMBL11696867 | 0.78 | MEN1 (0.49) | MEN1KMT2AMAPTALDH1A1ABCG2 | |
| SCHEMBL9525787 | 0.75 | MEN1 (0.72) | MEN1KMT2AMAPTALDH1A1ABCG2 | |
| SCHEMBL9525779 | 0.75 | MEN1 (0.72) | MEN1KMT2AMAPTALDH1A1ABCG2 | |
| SCHEMBL9525314 | 0.73 | MEN1 (1.00) | MEN1KMT2AMAPTALDH1A1ABCG2 | |
| SCHEMBL11696851 | 0.71 | CXCR2 (0.46) | MEN1KMT2AMAPTALDH1A1ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1707187-B1 | Reductive colorant for keratin fibres | WELLA AG (DE) | 2007-08-01 | — | — | EP | claimed |
| EP-1707187-A1 | Reductive colorant for keratin fibres | Wella Aktiengesellschaft (DE) | 2006-10-04 | — | — | EP | claimed |
| EP-1707187-B1 | Reductive colorant for keratin fibres | WELLA AG (DE) | 2007-08-01 | — | — | EP | disclosed |
| US-20060230548-A1 | Reductive colorant for keratin fibres | THE PROCTER & GAMBLE COMPANY | 2006-10-19 | — | — | US | disclosed |
| WO-2006107595-A1 | REDUCTIVE COLORANT FOR KERATIN FIBRES | THE PROCTER & GAMBLE COMPANY (US) | 2006-10-12 | — | — | WO | disclosed |
| EP-1707187-A1 | Reductive colorant for keratin fibres | Wella Aktiengesellschaft (DE) | 2006-10-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060230548-A1 | Reductive colorant for keratin fibres | KRT18, COX6C, CYC1 | MEN1 4140/4885KMT2A 994/4885MAPT 1101/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.