SCHEMBL9525779

SCHEMBL9525779

CC1=NN(c2ccc([N+](=O)[O-])cc2)C(=O)/C1=C/N

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 15/20 0.72
KMT2A Q03164 15/20 0.72
MAPT P10636 13/20 0.72
ALDH1A1 P00352 11/20 0.72
PKM P14618 2/20 0.72
ABCG2 Q9UNQ0 1/20 0.72
AMY1A P0DUB6 1/20 0.66
POLB P06746 3/20 0.61
LMNA P02545 5/20 0.52
KDM4E B2RXH2 5/20 0.52
TDP1 Q9NUW8 4/20 0.52
NPC1 O15118 3/20 0.52
SMN1; SMN2 Q16637 3/20 0.52
RAB9A P51151 2/20 0.52
HTT P42858 2/20 0.52
ALOX12 P18054 1/20 0.52
L3MBTL1 Q9Y468 6/20 0.50
USP2 O75604 1/20 0.50
HPGD P15428 4/20 0.47
THRB P10828 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9525787 1.00 MEN1 (0.72) MEN1KMT2AMAPTALDH1A1PKM
SCHEMBL9525314 0.84 MEN1 (1.00) MEN1KMT2AMAPTALDH1A1PKM
SCHEMBL29518154 0.81 MAPT (0.72) MEN1KMT2AMAPTALDH1A1PKM
SCHEMBL6733051 0.81 MEN1 (0.64) MEN1KMT2AMAPTALDH1A1PKM
SCHEMBL9525520 0.80 AMY1A (0.63) MEN1KMT2AMAPTALDH1A1AMY1A
SCHEMBL9525774 0.80 AMY1A (0.63) MEN1KMT2AMAPTALDH1A1AMY1A
SCHEMBL6952167 0.79 KDM4E (0.68) MEN1KMT2AMAPTALDH1A1PKM
SCHEMBL6952163 0.79 KDM4E (0.68) MEN1KMT2AMAPTALDH1A1PKM
SCHEMBL29183817 0.79 AMY1A (0.78) MEN1KMT2AMAPTALDH1A1PKM
SCHEMBL5190926 0.75 MEN1 (0.57) MEN1KMT2AMAPTALDH1A1PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0274642-B1 HERBICIDAL AND FUNGICIDAL AGENTS BASED ON SUBSTITUTED PYRAZOLIN-5-ONE DERIVATIVES BAYER AG (DE) 1993-08-11 EP claimed
US-5162528-A Pre- and post-emergence; phytaphthora in tomato plants; rice and wheat BAYER AKTIENGESELLSCHAFT (DE) 1992-11-10 US claimed
EP-0274642-B1 HERBICIDAL AND FUNGICIDAL AGENTS BASED ON SUBSTITUTED PYRAZOLIN-5-ONE DERIVATIVES BAYER AG (DE) 1993-08-11 EP disclosed